Answer the following questions based on the graph: a) Which of the two molecules that are the same size will passively diffuse across a cell membrane quicker? Why? [2 A] b) Which type of transport method would glucose use? Why? [2 A] Figure 1: Relative Sizes of Molecules Diffusing Across a Cell Membrane Substance Tested water oxygen glycerol glucose alcohol carbon dioxide 0 50 100 150 200 Relative Size of Molecules I
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- Answer the following questions based on the graph: a) Which of the two molecules that are the same size will passively diffuse across a cell membrane quicker? Why? [2 A] b) Which type of transport method would glucose use? Why? [2 A] Figure 1: Relative Sizes of Molecules Diffusing Across a Cell Membrane Substance Tested water oxygen glycerol glucose alcohol carbon dioxide Graph 50 100 Relative Size of Molecules 150 200Glucose transport across cell membranes varies depending upon blood glucose levels. When glucose levels are high, glucose transport is accomplished via membrane transporters. When glucose concentrations are low, the transport of glucose across the membrane is dependent upon the sodium ion concentration. What types of transport is observed for glucose? A)simple diffusion at high [glucose], secondary active transport at low [glucose] B)facilitated diffusion at high [glucose], secondary active transport at low [glucose] C)simple diffusion at high [glucose], primary active transport at low [glucose] D)facilitated diffusion at high [glucose], primary active transport at low [glucose]Name the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3 −) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms.What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?
- Name the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3−) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms. What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?A red blood cell with an intracellular fluid (ICF) concentration of 280 mmol/L, is placed into an environment were the concentration of the extracellular fluid (ECF) is 305 mmol/L. As a result, water will move across the cell/plasma membrane. a) Name the process by which water moves b) Describe the overall direction of movement of the water. Answer choices: (i) From outside the cell to inside the cell (ii) From inside the cell to outside the cell, or (iii) Equally, into and out of the cell iii Explain your reasoning for your answer to part (c). 1In your answer you must describe the environment on both sides of the membrane, and use 3 of the following 4 terms correctly; hypertonic, hypotonic, lower solute concentration, higher solute concentrationn (2pts -Correct use of biological terminology, and correct spelling is essential. Edit View Insert Format Tools Table 12pt v Paragraph BIUA ...In the stomach, parietal cells are responsible for the formation of the gastric juice. During acid secretion, the pH in the stomach is estimated to be pH = 2, whereas parietal cells maintain an intracellular pH =7.35. The transmembrane potential of parietal cells is typically -70 mV. Body temperature 37°C. 1) Calculate the proton gradient concentration across the parietal membrane 2) Calculate the free energy change associated with the secretion of 1 mole of H* 3) Do you think that Ht transport can be driven by ATP hydrolysis at the ratio of one molecule of ATP per H* transported? You can use your textbook or other sources to check AG for ATP hydrolysis 4) If H* where free to move back to into the cell, calculate the membrane potential that would be required to prevent them to do so
- While endocytosis and exocytosis refer to the direction in which a vesicle moves into and out of a cell respectively, it is important to think about what is being moved with and within the vesicles. To demonstrate how this process is utilized in human cells we will focus on the human body's insulin response. The purpose of the insulin response is to create a pathway for glucose entry into cells by releasing glucose transporters into the membrane. Cell Type #1- insulin producers: In humans, pancreatic B-cells create steroid insulin that can be packaged into vesicles starting at the ER. These vesicles are prepared for exocytosis so that the insulin can be released from the pancreatic B - cells and get into the bloodstream when signaled to do so. When glucose is present in the blood stream these cells will release the pre-packed insulin into the blood stream. Cell Type #2- insulin responders: Other cells do not produce insulin but instead respond when they have received the insulin signal…Estimate the flux (mg/cm2/s) by diffusion of estrogen (a steroid) through a lipid bilayer cell membrane when assuming the diffusion coefficient for estrogen across the lipid bilayer is 10^–6 cm2/s, and that the initial concentration of estrogen in the extracellular fluid is 1 ng/mL and 0 in the cytoplasm.Shown below are cells (colored) that were recently placed into a beaker containing a clear solution For each scenario, indicate whether movement of the molecule into the cell will occur using facilitated diffusion or active transport. А. B. 125mM 20mM fructose glucose 85MM 35mM fructose glucose OA= facilitated diffusion; B= facilitated diffusion OA= active transport; B= active transport O A= active transport; B= facilitated diffusion A= facilitated diffusion; B= active transport
- Describe what gap junction are, emphasizing on how they are different two other cellular points of contact, their protein components and cellular function. Describe the three main sources of membrane fluidity. Describe in detail what proteoglycans are, including their hygroscopicity and biological roles.Suppose the concentration of glucose inside a cell is 0.1 mM and the cell is suspended in a glucose solution of 0.01 mM. (a) What would be the free energy change involved in transporting 10-6 mole of glucose from the medium into the cell? Assume T = 37 °C. (b) What would be the free energy change involved in transporting 10-6 mole of glucose from the medium into the cell if the intracel- lular and extracellular concentrations were 1 mM and 10 mM, respectively? (c) If the processes described in parts (a) and (b) were coupled to ATP hydrolysis, how many moles of ATP would have to be hydrolyzed in order to make each process favorable? (Use the standard free energy change for ATP hydrolysis.)Phospholipid lateral motion in membranes is characterized by a diffusion coefficient of about 1 x 10-8 cm2/sec. The distance traveled in the membrane in a given time is r = √4Dt, where r is the distance traveled in centimeters is the diffusion coefficient, and t is the time during which diffusion occurs. Calculate the distance (in nanometers) traveled by a phospholipid in a bilayer in 25 msec (milliseconds).