Answer on Canvas: 1) Where does DOK1 localize in the cell? 2) Which region of DOK1 contains a nuclear export signal?

Q: 14) this is the serine protein kinase that when activated in a MPF complex that results in…

A: The cell cycle consists of the G1 phase, S phase, G2 phase, and mitotic phase, and is regulated by…

Q: The Bcl-2 protein was initially discovered via its ability to contribute to progression of B-cells…

A: Cancer is a disease caused by abnormal cell division.

Q: Name the roles that Anaphase Promoting Complex protein plays.

A: The Anaphase Promoting Complex (APC) is a multi-subunit protein complex that plays a crucial role in…

Q: Cancer cells generally have missense mutations in p53 gene, resulting in truncated p53 normally…

A: A normal cell is converted into a cancer cell when the there is deactivation of the tumor suppressor…

Q: Characterize the differences between tumor cells and normal cells in terms of the following…

A: A. The normal cell shows contact inhibition that means when two cells get contact then the growth…

Q: Explain why mutations in tumor suppressor genes are recessive (both copies of the gene must be…

A: Mutation in an organism is defined as a permanent alteration of “nucleotide sequences”. The…

Q: 10. When a primary signal needs to be sent to most cells throughout a multicellular organism, the…

A: The answers to the above questions are given below with explanation.

Q: Part A and B A. What is the normal function of the Rb protein? A) Rb prevents the cell cycle from…

A: Answer A) Rb is Retinoblastoma protein which is a tumor suppressor protein and belongs to pocket…

Q: The head of the oncology divison of a large biotech company proposes to develop a therapeutic…

A: For cancer treatment, there are several options. The treatment a patient receives depends on the…

Q: Discuss about cytokinesis

A: Cytokinesis : It is the physical process of cell division which divides the cytoplasm of a parental…

Q: which DNA binds to recipient cell at receptor site.?

A: The transfer of a gene from parents to offspring is called vertical gene transfer. The gene transfer…

Q: A mutated form of protein p5x is found in patients with squamous cell carcinoma. In vitro studies…

A: A gene that produces a protein that is essential for regulating cell division and death and is…

Q: Explain why IC3 is able to stop cancerous cells from dividing ?

A: Tumor-suppressor proteins are those proteins that normally act to stop abnormal cell growth. But…

Q: Using specific molecular evidence, elaborate on the remark "oocyte activation entails inactivation."

A: Egg activation refers to the early events that occur at fertilization and that start the development…

Q: "In the cellular regulatory pathways that control cell growth and proliferation, the products of…

A: Normal genes that are changed to become oncogenes are known as proto-oncogenes. They carry out a…

Q: What is the importance of determining the patient's onset of menses and the number of pregnancies?

A: MM is 54 year old female.  She is diagnosed with  intraductal adenocarcinoma of the left breast 5…

Q: How are “don’t eat me” signalseliminated or inactivated duringapoptosis to allow the cells to…

A: During phagocytosis, healthy cells secrete don't eat me the signal but theses signal needs to be…

Q: 20. In class, we discussed different types of genetic change that can cause a normal gene (proto…

A: There are two common causes of most cancers involves mutations in genes called proto-oncogenes and…

Q: 220. Dr. Rose Lees is a world expert on breast cancer. Choose True or False. Of all the receptors…

A: As per Bartleby policy i can solve only first question. The answer of first question - TRUE Cancer…

Q: Why would elevated levels of PSA be suggestive of prostate cancer given what you know about cancer?…

A: The prostate gland is situated below the urinary bladder and is responsible for the production of…

Q: Some studies have pointed that mutant p53 proteins have gained a novel function by inactivating…

A: P53 is an important protein that is considered a tumor-suppressing gene. The presence of p53…

Q: a) How does Venetoclax, a BH3 mimetic, function in increasing cellular death? In your answer make…

A: Venetoclax attaches to a protein called Bcl-2. This protein is present in high amounts in CLL cancer…

Q: Remember that DNA viruses inactivate tumor suppressor genes resulting in cancer. In Burkitt’s…

A: Translocation of c-myc occurs to one of the immunoglobulin foci. This leads to over expression of…

Q: Why is the p53-meditated apoptosis pathway, and the GSK3 signaling pathway important for cancer…

A: p53 is a critical tumour suppressor that is mutated in ~50% of human cancers. Inunstressed cells p53…

Q: // Which CDK and cyclin does p53 ultimately target in DNA damaged conditions? O CDK1/cyclin E O…

A: CDK phosphorylate soecific target proteins. They required cyclin to be activate. CDK-cyclin…

Q: Cancer cells are easier to maintain in culture than normal cells because a) they divide without the…

A: Cancer cells are mutated cells that are cultured in laboratories for studying various human…

Q: What would be the effect of a mutation that inactivates the p14ARF tumor suppressor upon p53…

A: p53 is known as a cellular tumor antigen 53 is a protein found in vertebrates that is responsible…

Q: Compare and contrast the intrinsic and extrinsic apoptosis pathways. Please keep brief - 3…

A: Apoptosis is an energy-dependent process of programmed cell death. It occurs normally during…

Q: ''In the cellular regulatory pathways that controlcell growth and proliferation, the products of…

A: Cell regulation involves a complex mechanism of different cell signaling pathways that work in a…

Q: components that are part of the synthesis of T3 T4?

A: Thyroid hormones are produced by thyroid glands which consists of thyroid follicles serving both as…

Q: Why is p53 considered a tumor suppressor protein?   Question 12 options:   a)  Because p53…

A: p53 is a tumor suppressor protein because it helps to prevent cells with damaged DNA from dividing.…

Q: Order the listed proteins in the correct order so that cell proliferation is activated as the…

A: HGF stimulates epithelial cell proliferation, motility, morphogenesis via tyrosine phosphorylation.…

Q: How does the epithelial-to-mesenchymal transition (EMT) contribute to tumorigenesis and disease…

A: Epithelial-mesenchymal transition (EMT) could be a method within which epithelial cells acquire…

Q: Explain the portion of the nuceloplasmin molecule responsible for localization in the nucleus.

A: Nuclear pore complexes or nucleoporins surround the nuclear pores in the nuclear membrane. Proteins…

Q: Synaptic vesicles release into the synapse to give the message to the post synaptic neuron?…

A: Synapses:  A synapse is a physical component of the nervous system that enables a neuron (or nerve…