Amino Acid Derivatives Q7.3: What explains the observation that individuals with phenylketonuria have pigmented skin and hair considering that phenylalanine hydroxylase catalyzes the conversion of phenylalanine to tyrosine and tyrosine is the precursor to melanin pigments?
Amino Acid Derivatives Q7.3: What explains the observation that individuals with phenylketonuria have pigmented skin and hair considering that phenylalanine hydroxylase catalyzes the conversion of phenylalanine to tyrosine and tyrosine is the precursor to melanin pigments?
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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BIOC 385
Amino Acid Derivatives
Q7.3: What explains the observation that individuals with phenylketonuria have pigmented skin and hair considering that phenylalanine hydroxylase catalyzes the conversion of phenylalanine to tyrosine and tyrosine is the precursor to melanin pigments?
Expert Solution
Step 1
Phenylketonuria is an inborn error of metabolism.
This disease is caused by mutations in the gene encoding phenylalanine hydroxylase that catalyzes the hydroxylation of phenylalanine to generate tyrosine.
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