The following are reactions encuntered in the metabolic cycles. Give the main class of enzymes that catalyzes these reactions1. Alanine + Oxoglutarate ---> Pyruvate +Glutamate AG --16,7 kJimol (Le. -30,5 • 13.8 kJ/mol)Hexokinaseor Glucokinase-(HOH)HOH)онMgATPADPD-GlucoseD-Glucose-6phosphateCH,OHH--OHÇH,OPO,HO--HHO--HO,POH,COH HонH-C-oHH--OHHHOH- -OHH--OHCH,OPO,CH,OPo,Glucose 6-phosphate(G-6P)Glucose 6-phosphate(open-chain form)Fructose 6-phosphate(open-chain form)Fructose 6-phosphate(F-6P)он+ NADH3C+ NADH + H'H3CононLactic AcidPyruvic AcidCH,OHCH,OHC=OC=Oн-с-онно-с—нн-с-онCH -OOн-с-онCH-ORibulose-5-phosphateXylulose-5-phosphate

1.Alanine+oxoglutarate ⇌ pyruvate+glutamate Alanine…

AG --16.7 kJimol (k.e. -30.5 • 13.8 kJ/mol) Hevokinase or G cokinase (HOH) он ADP D-Olucose D-Glucosephosphate CH,OH он OPo, o,POHE CH,OH но но H HỌ H C-oH H- -OH H -OH H--OH CH,OPo, CH,OPo, Glucose 6-phosphate (G-6P) Glucose 6-phosphate (open-chain form) Fructose 6-phosphate (open-chain form) Fructose 6-phosphate (F-6P) он + NAD + NADH + H H,C он он Lactic Acid Pyruvic Acid CH,OH CH,OH H-C-OH но-с—н н-с-он H-C-OH CH -OP CH-OP Ribulose-5-phosphate Xylulose-5-phosphate

AG --16.7 kJimol (k.e. -30.5 • 13.8 kJ/mol) Hevokinase or G cokinase (HOH) он ADP D-Olucose D-Glucosephosphate CH,OH он OPo, o,POHE CH,OH но но H HỌ H C-oH H- -OH H -OH H--OH CH,OPo, CH,OPo, Glucose 6-phosphate (G-6P) Glucose 6-phosphate (open-chain form) Fructose 6-phosphate (open-chain form) Fructose 6-phosphate (F-6P) он + NAD + NADH + H H,C он он Lactic Acid Pyruvic Acid CH,OH CH,OH H-C-OH но-с—н н-с-он H-C-OH CH -OP CH-OP Ribulose-5-phosphate Xylulose-5-phosphate

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Similar questions

The krebs cycle has 8 enzymes: citrate synthase, aconitase, isocitrate dehyrogenase, a-ketoglutarate dehydrogenase, succinyl –CoA synthease, succinate dehyrogenase, fumarase and malate dehyrogenase. a)Write name the cofactors required by each enzyme reaction. b)For each enzyme determine which of the following deascribes the type of reactions catalyzed: condensation (Carbon-carbon bond formation), dehydration (Loss of water), hydration (addition of water), decarboxylation (loss of CO2), oxidation-reduction; subsrate level phospohorylation; isomerization.
Explain why, glucose-6-phosphate will prefer to go via the pentose phosphate route. What additional chemical is created by this route, and what role does it play in anabolic pathways?
Referring to figure 5 and 8 which substrate molecule serves as the phosphate donor during substrate-level phosphorylation in step 10 of glycosis and the succinyl CoA-succinate step of the Krebs Cycle?
An investigator briefly incubates an actively respiring bacterial culture with [1-14 C]glucose and isolates the glycolytic and citric acid cycle intermediates. Where is 14 C located in each of the intermediates listed? Consider only the initial incorporation of 14C in the first pass of labeled glucose through the pathways. fructose 1,6-bisphosphate glyceraldehyde 3-phosphate phosphoenolpyruvate acetyl-CoA citrate ☐ ☐ ☐ ☐ ☐ ☐ ☐ a-ketoglutarate oxaloacetate Answer Bank C-4 C-1 C-3 C-2
Lactic acidosis, weakness, fatigue, and sleepiness are observed in patients with genetic defects of one if the enzymes of pyruvate dehydrogenase complex. Explain The causes of the elevation of lactate in the blood of such patients and the emergence of hypoenergetic state. For this purpose write the following: a) scheme of the metabolic pathway of glucose metabolism, that includes this reaction and calculates the energetic effect of the process, outlining the reactions coupled with the use and formation of ATP. b) reaction of the reduction of pyruvate and explain the reason for its acceleration inpatients that have such genetic defects.
Which of the following statements are False?
The first step of gluconeogenesis involves the carboxylation of pyruvate and has a large negative delta G (i.e very exergonic). Explain how it is possible that this step can be exergonic if we know that adding CO2 onto molecules is fundamentally a destabilizing phenomenon?
With the aid of diagrams and equations, explain the biochemical processes involved in each of the following, in named cells. Start by mentioning the purpose and site of securrence of each. Go in details please. (a) Glucose-alanine cycle. (b) Oxidative phosphorylation.
When the enzyme is incubated with oxaloacetate, will oxaloacetate be observed?