Hexokinase, the first enzyme of the glycolytic pathway, is capable of using both glucose and mannose as substrate. If the Km of the hexokinase for glucose is 3.43 x 10-3M and Km for mannose is 5.18 x 10-4M, which of the two substrates, glucose or mannose, will bind mor tightly to hexokinase? Selected Answer: glucose Correct Answer: lp Center? Question 11 Evaluation Method Exact Match BONUS The straight-line kinetic plot of 1/ Vo versus 1/[S] is called? Evaluation Method Exoct Motch Exact Match Thursday, August 13, 2020 8:47:09 PM CDT Question 7 Selected Answer: 3 km Correct Answer: Free Energy, G Ground state In the figure below, the "Gibbs free energy" of the reaction in presence of enzyme is represented by the letter: Transition state () Uncatalyzed Reaction --- Catalyzed Reaction Selected Answer: Answers: Ground state Reaction coordinate Selected Answer: 7 Correct Answer: Evaluation Method Exact Match Exact Match * Question 9 E A B C A D E D H₂N-CH CH ₂ C- H If PKR of HIS is 6.00, GLU is 4.25, and ASP is 3.65, calculate the charge on the following tripeptide at pH 4.0. The pK₁ for ASP is 1.88 and pK2 for HIS is 9.17 HIS GLU-ASP Correct Answer Mannose Selected Answer: 7 Correct Answer: Evaluation Method Exact Match Exact Match Exact Motch Correct Answer lineweaver Burk plot double reciprocal plot -N CH The pK₁. PKR, and pK2 values of histidine are 1.88, 6.00, and 9.17, respectively. Between what pH range (approximately) do you expect the structure of histidine shown here will exist in greatest amounts? Write your answer as pH and pH<_____ (high degree of difficulty question) COO- Correct Answer 0 Case Sensitivity zero Case Sensitivity Correct Answer > 6.00 and <9.17 >6<9 > 6 and <9 Case Sensitivity 10 poll Case Sensitivity U UULUT 10 poi

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Related questions
Question
Hexokinase, the first enzyme of the glycolytic pathway, is capable of using both glucose and mannose as substrate. If the Km of the
hexokinase for glucose is 3.43 x 10-3M and Km for mannose is 5.18 x 10-4M, which of the two substrates, glucose or mannose, will bind mor
tightly to hexokinase?
Question 11
Help Center?
Selected Answer: glucose
Correct Answer:
Evaluation Method
Exact Match
Question 7
www
Evaluation Method
Exact Match
Exact Match
Thursday, August 13, 2020 8:47:09 PM CDT
BONUS
The straight-line kinetic plot of 1/ Vo versus 1/[S] is called?
Selected Answer: km
Correct Answer:
Free Energy, G
Ground
state
In the figure below, the "Gibbs free energy" of the reaction in presence of enzyme is represented by the letter:
Transition state (:)
Ground
state
Reaction coordinate
Uncatalyzed Reaction
--- Catalyzed Reaction
Selected Answer:
Answers:
Selected Answer: 7
Correct Answer:
Evaluation Method
✔Exact Match
Exact Match
*
Question 9
G
E
A
B
C
D
A
E
H₂N-CH
CH ₂
If PKR of HIS is 6.00, GLU is 4.25, and ASP is 3.65; calculate the charge on the following tripeptide at pH 4.0. The pK₁ for ASP is 1.88 and pK2 for HIS is 9.17
HIS GLU-ASP
C.
H
B
Selected Answer: 7
Correct Answer:
Evaluation Method
Exact Match
Exact Match
Exact Match
Selected Answer: False
E
Correct Answer
Mannose
-N
Correct Answer
lineweaver Burk plot
double reciprocal plot
-N
The pK1. PKR, and pK2 values of histidine are 1.88, 6.00, and 9.17, respectively. Between what pH range
(approximately) do you expect the structure of histidine shown here will exist in greatest amounts?
Write your answer as pH>______ and pH< (high degree of difficulty question)
COO-
CH
Correct Answer
0
Case Sensitivity
zero
Case Sensitivity
Correct Answer
> 6.00 and <9.17
>6<9
> 6 and 9
Case Sensitivity
U OULUI To por
Case Sensitivity
Transcribed Image Text:Hexokinase, the first enzyme of the glycolytic pathway, is capable of using both glucose and mannose as substrate. If the Km of the hexokinase for glucose is 3.43 x 10-3M and Km for mannose is 5.18 x 10-4M, which of the two substrates, glucose or mannose, will bind mor tightly to hexokinase? Question 11 Help Center? Selected Answer: glucose Correct Answer: Evaluation Method Exact Match Question 7 www Evaluation Method Exact Match Exact Match Thursday, August 13, 2020 8:47:09 PM CDT BONUS The straight-line kinetic plot of 1/ Vo versus 1/[S] is called? Selected Answer: km Correct Answer: Free Energy, G Ground state In the figure below, the "Gibbs free energy" of the reaction in presence of enzyme is represented by the letter: Transition state (:) Ground state Reaction coordinate Uncatalyzed Reaction --- Catalyzed Reaction Selected Answer: Answers: Selected Answer: 7 Correct Answer: Evaluation Method ✔Exact Match Exact Match * Question 9 G E A B C D A E H₂N-CH CH ₂ If PKR of HIS is 6.00, GLU is 4.25, and ASP is 3.65; calculate the charge on the following tripeptide at pH 4.0. The pK₁ for ASP is 1.88 and pK2 for HIS is 9.17 HIS GLU-ASP C. H B Selected Answer: 7 Correct Answer: Evaluation Method Exact Match Exact Match Exact Match Selected Answer: False E Correct Answer Mannose -N Correct Answer lineweaver Burk plot double reciprocal plot -N The pK1. PKR, and pK2 values of histidine are 1.88, 6.00, and 9.17, respectively. Between what pH range (approximately) do you expect the structure of histidine shown here will exist in greatest amounts? Write your answer as pH>______ and pH< (high degree of difficulty question) COO- CH Correct Answer 0 Case Sensitivity zero Case Sensitivity Correct Answer > 6.00 and <9.17 >6<9 > 6 and 9 Case Sensitivity U OULUI To por Case Sensitivity
What is the name of the reactant, of the TCA cycle reaction, which yields a GTP?
Selected Answer: succinate
Correct Answer:
Evaluation Method
Exact Match
Question 11
Bnous:
Evaluation Method
Exact Match
Exact Match
Exact Match
onday, August 10, 2020 2:58:12 AM CDT
Which enzyme of the TCA cycle catalyzes the reaction similar to the one that converts pyruvate to acetyl CoA?
Selected Answer: dehydrogenase complex
Correct Answer:
Selected Answer: 2.5
Correct Answer:
Evaluation Method
Exact Match
✔ Exact Match
Selected Answer: False
Answers:
Question 10
Question 2
How many moles of NADH will be produced when 1 mole of fructose-1,3-bisphosphate is metabolized to pyuvate and then through TCA cycle
✔True
False
Selected Answer: succinate
Correct Answer:
Question 9
The TCA cycle enzyme fumarase catalyzes a reversiable reaction. This enzyme shows a very high degree of selectivity in choosing the
substrate for both the forward and the reverse reactions.
Evaluation Method
Exact Match
Specified Answer for: a
Specified Answer for: b
Correct Answers for: a
Evaluation Method
Exact Match
Correct Answers for: b
Evaluation Method
Exact Match
This enzyme,
What is the name of the reactant, of the TCA cycle reaction, which yields a GTP?
Evaluation Method
Exact Match
Exact Match
Selected Answer: phosphohexoese isomerase
Correct Answer:
isomerase
thiolase
A reaction of the glycolytic pathway is shown here.
Q O
H-OPO3²
CH₂OH
Specified Answer for: a
Specified Answer for: b
Correct Answers for: a
Question 2
The coordinated action of the enzymes [a] and [b] is needed for the metabolism of pyruvate to ethanol and CO₂.
1
Correct Answer
succinyl COA
cofactor
enolase
Correct Answer
alpha ketoglutarate dehydrogenase
alpha KG dehydrogenase
aKG dehydrgenase
10
Ten
00
Correct Answer
H₂C
-OPO-₂²
Correct Answer
succinyl COA
converts a phosphoryla hex into phosphorylated trioses
Case Sensitivity
Correct Answer
pyruvate decarboxylase
Correct Answer
alcohol dehydrogenase
Case Sensitivity
Case Sensitivity
Correct Answer
Fructose 1,6 bisphosphate aldolase
Aldolase
Case Sensitivity
Case Sensitivity
Case Sensitivity
In this reaction (marked as 1), the reactant undergoes [a] (describe the chemical process that occurs, e.g. oxidation) which is catalyzed by the
enzyme [b]. Identity of one product is not shown in this reaction.
Case Sensitivity
Transcribed Image Text:What is the name of the reactant, of the TCA cycle reaction, which yields a GTP? Selected Answer: succinate Correct Answer: Evaluation Method Exact Match Question 11 Bnous: Evaluation Method Exact Match Exact Match Exact Match onday, August 10, 2020 2:58:12 AM CDT Which enzyme of the TCA cycle catalyzes the reaction similar to the one that converts pyruvate to acetyl CoA? Selected Answer: dehydrogenase complex Correct Answer: Selected Answer: 2.5 Correct Answer: Evaluation Method Exact Match ✔ Exact Match Selected Answer: False Answers: Question 10 Question 2 How many moles of NADH will be produced when 1 mole of fructose-1,3-bisphosphate is metabolized to pyuvate and then through TCA cycle ✔True False Selected Answer: succinate Correct Answer: Question 9 The TCA cycle enzyme fumarase catalyzes a reversiable reaction. This enzyme shows a very high degree of selectivity in choosing the substrate for both the forward and the reverse reactions. Evaluation Method Exact Match Specified Answer for: a Specified Answer for: b Correct Answers for: a Evaluation Method Exact Match Correct Answers for: b Evaluation Method Exact Match This enzyme, What is the name of the reactant, of the TCA cycle reaction, which yields a GTP? Evaluation Method Exact Match Exact Match Selected Answer: phosphohexoese isomerase Correct Answer: isomerase thiolase A reaction of the glycolytic pathway is shown here. Q O H-OPO3² CH₂OH Specified Answer for: a Specified Answer for: b Correct Answers for: a Question 2 The coordinated action of the enzymes [a] and [b] is needed for the metabolism of pyruvate to ethanol and CO₂. 1 Correct Answer succinyl COA cofactor enolase Correct Answer alpha ketoglutarate dehydrogenase alpha KG dehydrogenase aKG dehydrgenase 10 Ten 00 Correct Answer H₂C -OPO-₂² Correct Answer succinyl COA converts a phosphoryla hex into phosphorylated trioses Case Sensitivity Correct Answer pyruvate decarboxylase Correct Answer alcohol dehydrogenase Case Sensitivity Case Sensitivity Correct Answer Fructose 1,6 bisphosphate aldolase Aldolase Case Sensitivity Case Sensitivity Case Sensitivity In this reaction (marked as 1), the reactant undergoes [a] (describe the chemical process that occurs, e.g. oxidation) which is catalyzed by the enzyme [b]. Identity of one product is not shown in this reaction. Case Sensitivity
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