Activity of phosphofructokinase-1 (PFK-1) is tightly-controlled by allosteric regulators. Identify the two positive and two negative allosteric regulators of PFK-1 activity from the list of biomolecules below. In addition, identify the two biomolecules in the list that do not function as allosteric regulators of PFK-1. Type of PFK-1 Regulation A. Positive allosteric regulation Biomolecules 1. fructose- 1,6-BP B. Negative allosteric 2. citrate regulation C. Not an allosteric 3. ATP regulator 4. ADP 5. glucose- 6P 6. fructose-

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.