Aarskog syndrome is a rare genetic condition affecting approximately 1/25,000 people. Researchers have found FGD1 gene mutations in approximately 22% of individuals with Aarskog syndrome. A study looking to establish causality reported an odds ratio for Aarskog syndrome of 2.24 (95% CI 1.2 to 3.45), comparing people with FGD1 mutations to those without. a) Provide a correct interpretation of this odds ratio b) Provide a plausible value for the risk ratio for Aarskog syndrome, comparing people with FGD1 mutations to those without. Why did you choose this value?

MATLAB: An Introduction with Applications
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Aarskog syndrome is a rare genetic condition affecting approximately 1/25,000 people. Researchers
have found FGD1 gene mutations in approximately 22% of individuals with Aarskog syndrome. A
study looking to establish causality reported an odds ratio for Aarskog syndrome of 2.24 (95% CI 1.2
to 3.45), comparing people with FGD1 mutations to those without.
a) Provide a correct interpretation of this odds ratio
b) Provide a plausible value for the risk ratio for Aarskog syndrome, comparing people with FGD1
mutations to those without. Why did you choose this value?
Transcribed Image Text:Aarskog syndrome is a rare genetic condition affecting approximately 1/25,000 people. Researchers have found FGD1 gene mutations in approximately 22% of individuals with Aarskog syndrome. A study looking to establish causality reported an odds ratio for Aarskog syndrome of 2.24 (95% CI 1.2 to 3.45), comparing people with FGD1 mutations to those without. a) Provide a correct interpretation of this odds ratio b) Provide a plausible value for the risk ratio for Aarskog syndrome, comparing people with FGD1 mutations to those without. Why did you choose this value?
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