nce exposur Ć Approximately 25% of mothe upon the incidence rate fc ates enrolling 100 case moth ecently conducted in another pod brain cancer given mate

MATLAB: An Introduction with Applications
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Author:Amos Gilat
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An epidemiologist is planning a case-control study to study the association
between farm residence exposure among pregnant women and childhood brain
cancer. Approximately 25% of mothers in the proposed study area live on a farm.
Based upon the incidence rate for childhood brain cancer, the investigator
anticipates enrolling 100 case mothers and 100 control mothers. A comparable
study recently conducted in another country reported a 2-fold odds ratio (OR) for
childhood brain cancer given maternal farm residence during pregnancy. The
investigator would like to ascertain if her/his sample size would be sufficient to
achieve at least 80% power to detect a 2-fold or greater OR for childhood brain
cancer for the proposed study.
Transcribed Image Text:An epidemiologist is planning a case-control study to study the association between farm residence exposure among pregnant women and childhood brain cancer. Approximately 25% of mothers in the proposed study area live on a farm. Based upon the incidence rate for childhood brain cancer, the investigator anticipates enrolling 100 case mothers and 100 control mothers. A comparable study recently conducted in another country reported a 2-fold odds ratio (OR) for childhood brain cancer given maternal farm residence during pregnancy. The investigator would like to ascertain if her/his sample size would be sufficient to achieve at least 80% power to detect a 2-fold or greater OR for childhood brain cancer for the proposed study.
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