The population frequency of Down’s syndrome children born to 25 yr old females is 1/1000. However if an ultrasound of the unborn child shows a nuchal translucency (a thickening on the back of the neck), the risk of Down’s syndrome is increased 15-fold, regardless of the mother’s age. Using Bayesian analysis, calculate the probability that a fetus with a nuchal translucency, conceived by a 25 yr old woman, will have Down’s syndrome. Give your answers as whole or decimal numbers (to three decimal places but you may provide up to 6 decimal places).   Scenario A – Down’s syndrome Scenario B - No Down’s syndrome Prior Probability     Cond. Probability     Joint probability     Posterior probability

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The population frequency of Down’s syndrome children born to 25 yr old females is 1/1000. However if an ultrasound of the unborn child shows a nuchal translucency (a thickening on the back of the neck), the risk of Down’s syndrome is increased 15-fold, regardless of the mother’s age. Using Bayesian analysis, calculate the probability that a fetus with a nuchal translucency, conceived by a 25 yr old woman, will have Down’s syndrome.

Give your answers as whole or decimal numbers (to three decimal places but you may provide up to 6 decimal places).

  Scenario A – Down’s syndrome Scenario B - No Down’s syndrome
Prior Probability    
Cond. Probability    
Joint probability    
Posterior probability    
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