A woman whose blood type is A- is planning on starting a family with a B+ blood type man. Which of the following is the most accurate advice that you could give to this couple based on their blood types? They should be concerned about hemolytic disease of the newborn for all of their pregnancies . Since the woman is Rh-, she produces anti-Rh antibodies. Since the man is Rh+, the fetus in all pregnancies with this man will also be Rh+. This means that the mom?s anti-Rh antibodies will destroy fetal RBCs every time that the woman gets pregnant, thus producing a dangerous anemia to all the fetuses from all pregnancies with this man. They should be concerned about hemolytic disease of the newborn. However, problems related to this condition seldom develop during a first pregnancy, because very few fetal cells enter the maternal bloodstream then, and thus the mother?s immune system is not stimulated to produce anti-Rh antibodies. However if a future pregnancy with the same man as the father occurs, maternal anti-Rh antibodies produced after the first delivery will cross the placenta and will enter the fetal bloodstream. These antibodies will destroy fetal RBCs, producing a dangerous anemia to this fetus. They should be concerned about hemolytic disease of the newborn. Since the woman is Rh-, she produces anti-Rh antibodies. However, since the woman is A type and the man is B type, it is less likely that this condition will affect the fetus in any of the pregnancies that this woman may have with this man. Since the man is B+ and the woman is A+, their babies will have 50% chances of being Rh-. If the fetus of one of the pregnancies was to inherit the Rh- trait, then and only then they should worry about hemolytic disease of the newborn. When this happens, the mother?s Rh+ antibody production can be prevented if anti-Rh+ antibodies (RhoGAM) are administered to the mother in weeks 26?28 of pregnancy and during and after delivery.
A woman whose blood type is A- is planning on starting a family with a B+ blood type man. Which of the following is the most accurate advice that you could give to this couple based on their blood types?
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They should be concerned about hemolytic disease of the newborn for all of their pregnancies . Since the woman is Rh-, she produces anti-Rh antibodies. Since the man is Rh+, the fetus in all pregnancies with this man will also be Rh+. This means that the mom?s anti-Rh antibodies will destroy fetal RBCs every time that the woman gets pregnant, thus producing a dangerous anemia to all the fetuses from all pregnancies with this man. |
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They should be concerned about hemolytic disease of the newborn. However, problems related to this condition seldom develop during a first pregnancy, because very few fetal cells enter the maternal bloodstream then, and thus the mother?s immune system is not stimulated to produce anti-Rh antibodies. However if a future pregnancy with the same man as the father occurs, maternal anti-Rh antibodies produced after the first delivery will cross the placenta and will enter the fetal bloodstream. These antibodies will destroy fetal RBCs, producing a dangerous anemia to this fetus. |
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They should be concerned about hemolytic disease of the newborn. Since the woman is Rh-, she produces anti-Rh antibodies. However, since the woman is A type and the man is B type, it is less likely that this condition will affect the fetus in any of the pregnancies that this woman may have with this man. |
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Since the man is B+ and the woman is A+, their babies will have 50% chances of being Rh-. If the fetus of one of the pregnancies was to inherit the Rh- trait, then and only then they should worry about hemolytic disease of the newborn. When this happens, the mother?s Rh+ antibody production can be prevented if anti-Rh+ antibodies (RhoGAM) are administered to the mother in weeks 26?28 of pregnancy and during and after delivery. |
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