A couple decide to have a child. They require and select a suitable sperm donor who they understand to be blood group AB and rhesus +ve. The carrier of the baby is blood group A and rhesus –ve. However, when the baby is born, they discover that the baby’s blood group is O rhesus +ve. Worried that there has been a mistake they ask for a DNA test, which confirms the sperm used was indeed that of the donor. Further DNA analysis of the carrier of the baby shows that she has isoagglutinogen alleles IA iO, while the baby is actually IB and IO. How would you explain the outcome of the blood group to the couple?What is the chance that any other children will be blood group O using the same sperm donor? What further medical considerations should the couple consider for this child and additionally for any other subsequent pregnancies?

The blood group of a person is decided by the presence or absence of particular antigens on the…

Answered: A couple decide to have a child. They…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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A couple decide to have a child. They require and select a suitable sperm donor who they understand to be blood group AB and rhesus +ve. The carrier of the baby is blood group A and rhesus –ve. However, when the baby is born, they discover that the baby’s blood group is O rhesus +ve. Worried that there has been a mistake they ask for a DNA test, which confirms the sperm used was indeed that of the donor. Further DNA analysis of the carrier of the baby shows that she has isoagglutinogen alleles I^A i^O, while the baby is actually I^B and I^O.

How would you explain the outcome of the blood group to the couple?

What is the chance that any other children will be blood group O using the same sperm donor?

What further medical considerations should the couple consider for this child and additionally for any other subsequent pregnancies?

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