A receptor, R, binds to its ligand, L, according to the binding curve shown below. If [R]= 30 mM at the KD, what is the concentration of the receptor-ligand complex at the KD? 1.0 Q2 10 15 20 25 30 35 40 45 50 55 60 0 0.5 40 mM O 25 mM O 30 mM O 10 mM 17.5 ml 5 [Ligand] (mm)

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter6: Oral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 9.4P
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Question
A receptor, R, binds to its ligand, L, according to the binding curve shown below. If
[R]= 30 mM at the KD, what is the concentration of the receptor-ligand complex at
the KD?
1.0
Q2
10 15 20 25
30 35 40 45 50 55 60
0 0.5
40 mM
O 25 mM
O 30 mM
O 10 mM
17.5 ml
5
[Ligand] (mm)
Transcribed Image Text:A receptor, R, binds to its ligand, L, according to the binding curve shown below. If [R]= 30 mM at the KD, what is the concentration of the receptor-ligand complex at the KD? 1.0 Q2 10 15 20 25 30 35 40 45 50 55 60 0 0.5 40 mM O 25 mM O 30 mM O 10 mM 17.5 ml 5 [Ligand] (mm)
You are evaluating the kinetics of an enzyme catalyzed reaction containing 5.5 μM total enzyme and 11.2
μM substrate. At this substrate concentration, you determine that the
Vo = 88.6 μmol mL-¹. s-¹. If the Vmax
833.3 mM s the KM is:
.
==
"
30.9 μΜ
10.4 μΜ
Ο 124.6 μΜ
234 μΜ
94.5 μM
Transcribed Image Text:You are evaluating the kinetics of an enzyme catalyzed reaction containing 5.5 μM total enzyme and 11.2 μM substrate. At this substrate concentration, you determine that the Vo = 88.6 μmol mL-¹. s-¹. If the Vmax 833.3 mM s the KM is: . == " 30.9 μΜ 10.4 μΜ Ο 124.6 μΜ 234 μΜ 94.5 μM
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