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A protein has a mutation of a glycine to a lysine. Whát kind of mu tion Is th H HN *NH3 Glycine Lysine O Nonsense O Missense O Silent O Frameshift

A protein has a mutation of a glycine to a lysine. Whát kind of mu tion Is th H HN *NH3 Glycine Lysine O Nonsense O Missense O Silent O Frameshift

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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### Protein Mutation: Glycine to Lysine A protein has a mutation of a glycine to a lysine. What kind of mutation is this? #### Structures: - **Glycine:** - Structure is shown with a simple amino acid backbone, consisting of an amino group (\(^+\text{H}_3\text{N}\)), a carboxyl group (\(\text{O}^-\)), and a hydrogen atom as the side chain. - **Lysine:** - Structure is shown including an amino group (\(^+\text{H}_3\text{N}\)), a carboxyl group (\(\text{O}^-\)), and a longer side chain terminating in an additional amino group (\(^+\text{H}_3\text{N}\)). #### Mutation Types: - **Nonsense** - **Missense** - **Silent** - **Frameshift** **Question:** Identify the type of mutation from the list above based on the change from glycine to lysine. **Note:** Understand the effect of each mutation type: - **Nonsense:** Results in a premature stop codon. - **Missense:** Results in one amino acid being replaced by another. - **Silent:** Does not result in an amino acid change. - **Frameshift:** Results from insertions or deletions altering the reading frame.
Transcribed Image Text:### Protein Mutation: Glycine to Lysine A protein has a mutation of a glycine to a lysine. What kind of mutation is this? #### Structures: - **Glycine:** - Structure is shown with a simple amino acid backbone, consisting of an amino group (\(^+\text{H}_3\text{N}\)), a carboxyl group (\(\text{O}^-\)), and a hydrogen atom as the side chain. - **Lysine:** - Structure is shown including an amino group (\(^+\text{H}_3\text{N}\)), a carboxyl group (\(\text{O}^-\)), and a longer side chain terminating in an additional amino group (\(^+\text{H}_3\text{N}\)). #### Mutation Types: - **Nonsense** - **Missense** - **Silent** - **Frameshift** **Question:** Identify the type of mutation from the list above based on the change from glycine to lysine. **Note:** Understand the effect of each mutation type: - **Nonsense:** Results in a premature stop codon. - **Missense:** Results in one amino acid being replaced by another. - **Silent:** Does not result in an amino acid change. - **Frameshift:** Results from insertions or deletions altering the reading frame.
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