A new water-soluble anti-diabetic drug with a molecular weight of 210.2 g/mol has an absorption maximum at 278 nm and a molar absorptivity (ε) of 6.15 x 103 M-1cm-1.   One tablet of the drug was crushed and quantitatively transferred to a 100 mL volumetric flask and the flask was filled to the mark with deionized water. This solution had an absorbance of 0.770 at 278 nm in 1.00-cm cell.   A blank was prepared by treating a tablet with identical composition but without the anti-diabetic drug in an identical manner. The absorbance of this blank solution was 0.052 at 278 nm in a 1.00-cm cell.   (Show your work)   a. Calculate the concentration of the final solution from Beer’s Law.     b. Calculate the mass in mg of the anti-diabetic drug in the tablet.

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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A new water-soluble anti-diabetic drug with a molecular weight of 210.2 g/mol has an absorption maximum at 278 nm and a molar absorptivity (ε) of 6.15 x 103 M-1cm-1.

 

One tablet of the drug was crushed and quantitatively transferred to a 100 mL volumetric flask and the flask was filled to the mark with deionized water. This solution had an absorbance of 0.770 at 278 nm in 1.00-cm cell.

 

A blank was prepared by treating a tablet with identical composition but without the anti-diabetic drug in an identical manner. The absorbance of this blank solution was 0.052 at 278 nm in a 1.00-cm cell.

 

(Show your work)

 

a. Calculate the concentration of the final solution from Beer’s Law.

 

 

b. Calculate the mass in mg of the anti-diabetic drug in the tablet.

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