A loss-of-function mutation in the ion channel responsible for the generation of end-plate potentials results in a diminished permeability of the ion channel.  1)  How would you experimentally test the effect of the mutation on the functional properties of the cell (synapse)? You should discuss the types of postsynaptic responses and physiological parameters you could measure.

Q: A neuron with a resting membrane potential of -75 mV receives multiple inputs giving rise to the…

A: The action potential is a condition of a nerve impulse or electrical activity when there is a…

Q: A graded potential that achieves threshold leads to the generation of an action potential. Which one…

A: Graded potentials are made by outside stimuli in sensory neurons or by neurotransmitters discharged…

Q: Which of the following statements regarding action potentials is false? Na+ channel inactivation is…

A: 1. Na+ channel inactivation is due to a voltage-dependent block of the channel pore.This is true.…

Q: a) Explain in detail what is occurring at stage A in the graph. (Be specific in terms of what's…

A:

Q: Dr. Brainy creates a nerve cell that is only permeable to Caesium ions (Cs+1) at rest. She measures…

A: Option a: This option is incorrect because This value signifies that there's no driving force for…

Q: You are recording the electrical activity of a cell body with a resting membrane potential of -70…

A: Given; Resting membrane potential of the cell= -70mV No. of stimuli detected by the cell= 3 from…

Q: Some neurons have very long dendritic arbors. Scientists wanted to understand how synaptic currents…

A: The study of neuronal dendrites and their part in action potential generation is an interesting area…

Q: Which of the following is one major difference? [Choose ] Only action potentials cause…

A: There is difference in the concentration of ions inside and outside the each cell of body and this…

Q: Predatory cone snails are beautiful (picture below), but deadly - they release a cocktail of toxins…

A: The neurons have the capability of generation of action potential and also transferred this action…

Q: Which is TRUE about neuronal membrane electrical and concentration gradients at the peak of the…

A: An action potential is sudden and transient changes in the voltage across a biological membrane. It…

Q: 3. Electrical Signal: The Action Potential In the figure to the left, name the 4 phases of the…

A: Action potential refers to a fast, propagating change in the resting membrane potential of a cell.…

Q: Describe the sequence of events that occur after a stimulus depolarizes the membrane from resting…

A: The resting potential tells about what happens when a neuron is very still or at rest. An action…

Q: Why does neuronal function require the voltage-gated K+ channels to open more slowly than the…

A: Voltage-gated channels are specialized proteins that are essential for the generation and…

Q: What is the expected resting membrane potential (in mV) of a neuron that is typical in all ways…

A: The membrane potential is a term that signifies the distribution of opposite charges across the…

Q: - In terms of Na and K ion gradient /movement - what causes the action potential (positive charge…

A: The Na+ K+ ion gradient refers to the concentration difference of sodium (Na+) and potassium (K+)…

Q: If the plasma membrane of an electrically excitable cellwere depolarized to threshold in the center…

A: An action potential is defined as a swift increase that is followed by a drop in the voltage or…

Q: atch the description with the statement that best describes the following statements…

A: When a cell is not stimulated, its resting membrane potential is defined as the electrical potential…

Q: In Japan, the consumption of “Fugu” (a kind of sashimi sushi) is considered to be a “manly” act. The…

A: Fugu is a type of pufferfish that is considered a delicacy in Japan. It is typically served as…

Q: The sodium-potassium pump is really important to the functioning of neurons. (a) What does it do?…

A: The neurons in the nervous system have the capability of producing and conducting electrical…

Q: Besides the standard post- and pre-synapse that exchange information, non neuronal cell types also…

A: Astrocytes are cells having distinct morphological and functional characteristics present within…

Q: Would anyone be able to explain these different channels? I would like an explanation as to why…

A: All ion channels are primarily located at their respective sites depending on their response to that…

Q: mbing fiber depolarizes mbrane potential to en Ca2+ channels. tage-gated channel 2+ Ca²+ Release 2+…

A: The objective of the question is to identify the most direct mechanism causing the postsynaptic…

Q: 3) You are investigating the ionic selectivity of an ion channel opened by activation of a specific…

A: A.                                   E(K+)= RTnFlnOUTIN=8.314×2981×96485ln5140=-0.089≈-89mV…

Q: If neurons fire action potentials when membrane potential reaches -50mV, how would hyperkalemia…

A: Hyperkalemia is a medical condition where there is an excess of potassium ions (K+) in the…

Q: Describe the “all-or-none” principle of action potentials. Does the restoration of a resting…

A: In human physiology, the phenomena of action potential refers to the rapid changes in the membrane…

Q: Ordinarily, a neuron’s trigger zone is activated before any other part ofan axon, so a wave of…

A: Nerve cells are electrically excitable cells that method and transmits information by electrical and…

Q: 60. The action potential of a normal axon is shown on the graph. K* conductance is maximal at which…

A: Introduction :- An action potential (AP) is defined as a rapid rise and fall in the membrane…