A geneticist has two true-breeding strains of mice. Each strain is homozygous for an independently discovered dominant mutation that causes the mice to have no fur. One mutant strain is called “hairless”, and the other strain is called “naked”. The geneticist crosses hairless and naked mice with each other and the F1 offspring all have no fur. When the F1 mice are crossed with each other, the offspring consist of 187 mutant mice with without fur and 13 normal mice with fur. a.      Are the “hairless” and “naked” mutations alleles of the same gene? Give a reason for your answer. b.    Give the genotypic and associated phenotypic ratios of the F2 offspring. (which genotypes in the offspring of the F1 x F1 cross produce fur and which genotypes produce no fur).

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A geneticist has two true-breeding strains of mice. Each strain is homozygous for an independently discovered dominant mutation that causes the mice to have no fur. One mutant strain is called “hairless”, and the other strain is called “naked”. The geneticist crosses hairless and naked mice with each other and the F1 offspring all have no fur. When the F1 mice are crossed with each other, the offspring consist of 187 mutant mice with without fur and 13 normal mice with fur.

a.      Are the “hairless” and “naked” mutations alleles of the same gene? Give a reason for your answer.

b.    Give the genotypic and associated phenotypic ratios of the F2 offspring. (which genotypes in the offspring of the F1 x F1 cross produce fur and which genotypes produce no fur)

In another strain of mice, coat colour is controlled by a single gene with multiple alleles in a dominance series where cream (A1) > agouti (A2) > brown (A3) > black (A4).

c. Give the genotypes of two phenotypically different heterozygotes that when crossed produce offspring with the phenotypic ratio of 1 agouti : 2 cream : 1 black 

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