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Name: To determine the number of genes potentially involved in eye developme
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Description: To determine the number of genes potentially involved in eye development in mice, you perform a screen of mutant mice (having no eyes). You isolate 10 strains of mice with no eyes (Line 1 to Line 10) each of which is homozygous recessive). You then p

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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To determine the number of genes potentially involved in eye development in mice, you perform a screen of mutant mice (having no eyes). You isolate 10 strains of mice with no eyes (Line 1 to Line 10) each of which is homozygous recessive). You then perform crosses between all strains and obtain the following results where the “-“ phenotype indicates mouse without eyes and a “+” phenotype represents offspring with eyes. The “??” are not known at this time.

Based on the data, i) determine the complementation groups and ii) the number of genes potentially involved in the production of eyes in mice?

Line 1 | Line 2
Line 3
Line 4
Line 5 Line 6
Line 7
Line 8
Line 9
Line 10
Line 1
Line 2
+
Line 3
??
Line 4
+
Line 5
??
Line 6
+
Line 7
+
??
??
+
Line 8
??
+
+
+
Line 9
+
+
+
+
+
+
Line 10
Wild -
+
+
+
type
+
+
+
+
+
+
+
+
+
+ +
+
+
+
+
+
+
+

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