A couple enters your genetic counseling clinic for some family planning advice. The woman’s father was color blind, but her own vision is normal. The man has no family history of color blindness. Neither the man nor woman have any known history of hemophilia, but their first child (a boy) has hemophilia. They ask you to calculate the chance that their next child will be affected by one or both conditions. You remember from your genetics training that these are both X-linked recessive conditions and that they are closely linked: in fact, their genetic loci are separated by only 10cM! During the interview with this couple, you draw the following pedigree to represent their information. Given what you know, determine for this couple what chance they have of each of the following (in the table).

Q: As a genetic counselor, you are asked to assess the risk for a couple with a family history of…

A: Familial adenomatous polyposis is an inherited disease that is autosomal dominant and results in…

Q: 33. (recall) Which of the following STATEMENTS about genes is incorrect? A) Genetic differences can…

A: DNA is the genetic material present in the cells of living beings.

Q: Create a hypothetical person and situation as a real life example to illustrate your position. Who…

A: Z is a 31-year-old male and he wishes to marry. He is the only child of his parents. His fiancé B…

Q: estions below all refer to the following pedigree. The locus for allele D/d determines how cilia on…

A: It is evident that the trait is not sex-linked because:-   In the case of Y-linked disorders, only…

Q: A family with a history of a genetic disorder were analyzed with a dot blot using a probe for both…

A:

Q: Explain at the biochemical or enzymatic level, the phenotypic consequences of alleles incase of…

A: This is the phenomenon called incomplete dominance which is usually seen in snapdragons. In the…

Q: Consider Dr. Whitt’s comments about the relationship between the wild-type and mutant RB1 alleles…

A: Cancers are caused by loss of control over cell division, which leads to uncontrolled cell division…

Q: 1. This pedigree tracks the inheritance of freckles, an autosomal dominant trait, for 3 generations.…

A: In this question, we are shown a pedigree of autosomal dominant trait which is showing inheritance…

Q: A genetic disorder is caused by a LOF mutation (Bm) and epigenetic imprinting of gene B. Through…

A: Epigenetic imprinting or genomic imprinting is a process where there is the exclusive expression of…

Q: Pedigree information regarding the incidence of Tay-Sachs within a family is depicted above. The row…

A: We may establish genotypes, classify phenotypes, and predict how a trait will be transferred down in…

Q: A research team genotyped hundreds of families affected by haemophilia. Among those families, they…

A: RFLP is found on X chromosome and it is a sex-linked recessive disorder. The daughter who inherited…

Q: Codominance ABO blood typing is an example of codominance, where A and B are both dominant to O. A…

A: In ABO blood typing, the allele IA is dominant over i. Similarly, the allele IB is dominant over i.…

Q: A girl is taking a genetics course on the ABO blood types where she learns that she has an O blood…

A: Blood is a connective tissue found in many living organisms. It is constantly circulating fluid…

Q: The pedigree below shows the inheritance pattern of a rare X-linked allele for one family. The…

A: Pedigree is a family chart where genetic councillor put some symbol for easy description of a…

Q: You are a genetic councilor and your first patients of the day have arrived. They have both tested…

A: Cystic fibrosis is a hereditary disease that affects the lungs and digestive system. The body…

Q: The genes for hemophilia, a condition that causes blood not to clot properly, are located on the X…

A: Inheritance patterns are of different type’s   Mendelian inheritance, incomplete dominance,…

Q: The p value resulting from a Chi squared test tells you a)Mendel's ratios. b)how many degrees of…

A: A Chi-square test is a way of quantifying the various deviations expected by chance if a hypothesis…

Q: At Elmhurst hospital in Queens, a couple originally from the South Indian city of Bengaluru bring…

A: The situation in the waiting room of Elmhurst Hospital in Queens is tense. A couple originally from…

Q: evidence suggests that spherocytosis is incompletely penetrant?

A: Spherocytosis is a condition that affects red blood cells. People suffering from spherocytosis…

Q: A couple wants to have a child, but the mother has a brother that is affected by cystic fibrosis.…

A: Introduction  Cystic Fibrosis Is An Autosomal Recessive Hereditary Condition Marked By The…

Q: You've been having trouble sleeping because of your obsession with understanding the Rh factor (+…

A: Red blood cells(RBCs) consist of different antigens on their surface. The presence of these antigens…

Q: A RFLP is discovered that is linked to the gene for Duchenne’s muscular dystrophy (DMD). DMD is an…

A: RFLP (Restriction Fragment length polymorphism) : RFLP (Restriction Fragment length polymorphism is…

Q: Solve the following genetics problem: (1)Assume that you are a lawyer working in a family law and…

A: Gene is a particular segment of DNA (deoxyribonucleic acid) that is responsible for the inheritance…

Q: A genetics counselor, Nashaly Montez, notices an odd pattern in Devin’s pedigree, a propensity for…

A: Translation is a biological process that occurs in cells, during which the genetic information…

Q: 22. State how many children or percent that can be normal pigmented with dwarfism (A_D_). 23. State…

A: Autosomal inheritance means the inheritance or passing of the genetic trait from parents to…

Q: he propensity to develop retinal cancer can run in pedigrees of certain families. You have learned…

A: Tumor suppressor genes are important cancer prevention genes since a partial or total inactivation…

Q: 8 7 6 5 2 3 II I-1 1-2 2 1 2 3 4 5 6 7 8 [= II-1 11-2 11-4 II-5 11-6 II-7 II-8 11-3

A: Pedigree - Pedigree analysis is a chart that represents a family tree, which displays the members…

Q: PowerPoint presentation on this topic " Prenatal Molecular Testing ". I have total 4 members in my…

A: Slide 1: Title SlideTitle: Prenatal Molecular TestingYour NameDateSlide 2: IntroductionDefinition of…

Q: A couple comes to you, a genetics counselor, asking for you to explain to them their risk of having…

A: Cystic fibrosis is caused by a change, or the mutation, in a gene called CFTR (cystic fibrosis…

Q: My professor instructed me to make a power point presentation on this topic" Prenatal Molecular…

A: Prenatal molecular testing is a collection of advanced genetic tests and techniques used during…

Q: in certain fish, the mating of a black (B) fish with a white (W) fish will create offspring with a…

A: Since you have posted multiple questions we solve the first question for you. To get the remaining…

Q: m having trouble with my genetics study guide, and am stuck on this question. If someone could…

A: Blood type can be classified on the basis of the presence and absence of antibodies and antigens on…

Q: 1-C-yonce is type B. What must her genotype be? 2-What must Kay-Z’s genotype be? 3-Which parent…

A: Blood types are determined by the presence or absence of certain proteins called antigens on the…

Q: A genetic counsellor is working with a couple who have just had a child who has a debilitating…

A: Epidermolysis bullosa or EB is a rare inherited skin disease. It is an autosomal recessive disease,…

Q: Following figure is showing the DNA fingerprint analysis on the ônë locus öf å man with four…

A: DNA fingerprinting is a test which uses Dna of a person at generate its fragments.

Q: A genetics counselor, Nashaly Montez, notices an odd pattern in Devin’s pedigree, a propensity for…

A: Tumor suppressor genes function to control cellular proliferation by negatively regulating cell…

Q: 2a. The pedigree below represents inheritance of rare condition. What pattern of inheritance is most…

A: A pedigree chart is made which indicates the various relationships in a family and with reference to…

Q: Cystic fibrosis (CF) is an autosomal recessive trait. A three-generation pedigree is shown below for…

A: Given: Cystic fibrosis (CF) is an autosomal recessive trait. Normal allele =  F      CF mutant…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.