A genetic mutation leads to reduced function/loss of function of the V-ATPase on the surface of cellular lysosomes. Explain the role of the V-ATPase on the lysosomal membrane and the possible consequences of the reduced/lost function of this membrane protein.

Q: With regard to cytoskeletal structure and function, a) Outline the structure and organisation of…

A: The cytoskeleton is the web of fibres that makes up eukaryotic, prokaryotic, and archaeal cells.…

Q: Dynamic instability is the phenomenon by which microtubules undergo rapid growth and disassembly.…

A: Dynamic instability is the phenomenon by which microtubules undergo rapid growth and disassembly.…

Q: describe in detail the pathway of lysosomal enzyme from the endoplasmic reticulum to the lysosome

A: Lysosomes are tiny vesicles with hydrolytic enzymes that are separated by a single membrane. Because…

Q: Anticancer drugs that affect microtubules are often used in cancer treatment. Explain why this is…

A: Anticancer drugs that affect microtubules are often used in cancer treatment. Explain why this is…

Q: In many different human diseases, there is an abnormal accumulation of mis-folded proteins within…

A: There is a molecular pathway implicated in various neurodegenerative diseases is the misfolding,…

Q: There are several regulation mechanisms for the progression of a cell through the cell cycle and for…

A: Cyclin - dependent kinases (Cdks) and cyclins are the proteins, that drive  and regulate cell cycle.…

Q: With regard to cytoskeletal structure and function, describe the molecules involved in the transport…

A: The endoplasmic reticulum is an organelle that plays a crucial role in protein and lipid synthesis,…

Q: Choose the correct order of events for protein synthesis of an INTEGRAL MEMBRANE PROTEIN. 1.…

A: Gene expression is the process by which information from a gene is used in the synthesis of a…

Q: A mutated form of protein p5x is found in patients with squamous cell carcinoma. In vitro studies…

A: A gene that produces a protein that is essential for regulating cell division and death and is…

Q: Microtubules both in vitro and in vivo undergo dynamic instability, and this type of assembly is…

A: Microtubules are structures composed of tubulin protein.

Q: Describe the process of protein synthesis and trafficking of a protein, a lysosomal hydrolase,…

A: The targetting of specific protein depends on their mode of synthesis. The proteins of lysosome,…

Q: Please help me with this question. More than one answer may be correct.  The rough endoplasmic…

A: The endoplasmic reticulum performs numerous other crucial tasks, including folding proteins, but it…

Q: Taxol, derived from the Pacific Yew tree, was one of the first effective anti-cancer compounds…

A: Taxol is an anti-cancer chemotherapy drug.Taxol is classified as a "plant alkaloid".It is an…

Q: Discuss the pathway that secretory proteins (proteins destined to leave the cell) take through the…

A: protein synthesis occur in ribosome structure and after protein synthesis, protein modification…

Q: Explain a mechanism for how a nuclear-encoded protein is targeted to the inner membrane of the…

A: Mitochondria possess specific replication, transcription, and translation machinery. All the…

Q: Disorder 2 is associated with the..... Group of answer choices mitochondria peroxisome ribosome…

A: Disorder 2: Some people are born with or acquire a gene mutation that causes a certain defective…

Q: How does M-Cdk promote Golgi breakdown during mitosis? Prevents COPI vesicle fusion to the Golgi…

A: M-Cdk is a cyclin-dependent protein kinase. It will catalyze the transfer or transmission of a…

Q: Tab. 6. Mechanisms of intracellular accumulation of substances (Intracellular Accumulations or…

A: It is critical to understand how cells collect substances inside them in order to analyze and treat…

Q: The best strategy for treating a specific type of human tumor can depend on identifying the type of…

A: Part A. IFS are the ones that provide abundant buffering system in order to protect against…

Q: Described below are a collection of five human diseases/disorders, each associated in some way with…

A: Zellweger spectrum disorders (ZSD) includes three disorders namely Zellweger syndrome, Neonatal…

Q: If cells are treated with colchicine, a drug that promotes microtubule disassembly, the location of…

A: Microtubules in cells are assembled usually at the Microtubule Organizing Center (MTOC). MTOC…

Q: Proteins that are trafficked through the secretory pathway of eukaryotic cells are never exposed…

A: Option A is wrong because cells that specialize in protein secretion has cytoplasm.

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.