Described below are a collection of five human diseases/disorders, each associated in some way with a cellular organelle. Based on these descriptions and your knowledge of the structure and function of cellular organelles, identify the organelle that is associated with each disorder.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Disorder 5 is associated with the.....
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peroxisome
ribosome
endoplasmic reticulum
mitochrondria
Described below are a collection of five human diseases/disorders, each associated in some
way with a cellular organelle. Based on these descriptions and your knowledge of the structure
and function of cellular organelles, identify the organelle that is associated with each disorder.
Transcribed Image Text:Described below are a collection of five human diseases/disorders, each associated in some way with a cellular organelle. Based on these descriptions and your knowledge of the structure and function of cellular organelles, identify the organelle that is associated with each disorder.
Disorder 5:
These disorders are a large group of genetic disorders (some can also be considered "inborn
errors of metabolism"). These conditions vary in symptoms and age of onset. However, they
share a problem with the functioning of a certain organelle, one of the smallest within the cell.
Some of the issues are break-down (beta-oxidation) of very long chain fatty acids, hydrogen
peroxide detoxification, and the synthesis (production) of cholesterol, bile acids, and
plasmalogens. The myelin (or "white matter") of the brain is composed of phospholipids made
from cholesterol. Because myelin production can be disrupted in some of these disorders, they
are also classified as white matter disorders, or leukodystrophies. The hallmark of these
disorders is an accumulation of very long chain fatty acids as well as accumulation of bile-acids.
Transcribed Image Text:Disorder 5: These disorders are a large group of genetic disorders (some can also be considered "inborn errors of metabolism"). These conditions vary in symptoms and age of onset. However, they share a problem with the functioning of a certain organelle, one of the smallest within the cell. Some of the issues are break-down (beta-oxidation) of very long chain fatty acids, hydrogen peroxide detoxification, and the synthesis (production) of cholesterol, bile acids, and plasmalogens. The myelin (or "white matter") of the brain is composed of phospholipids made from cholesterol. Because myelin production can be disrupted in some of these disorders, they are also classified as white matter disorders, or leukodystrophies. The hallmark of these disorders is an accumulation of very long chain fatty acids as well as accumulation of bile-acids.
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