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A gene in the fruit fly D. melanogaster is found to affect neuronal function when mutated. A homologue of this gene is identified in mice (e.g. a gene likely descended from a last common ancester). Which of the following methods would it make most sense for a scientist to use to study the function of the gene in mice? Check all that apply. O CRISPR-Cas9 genome editing targeting the gene of interest followed by homologous recombination (HR) with a donor template O Reverse genetics O Whole genome sequencing OCRISPR-Cas9 genome editing targeting the gene of interest followed by nonhomologous end joining (NHEJ)

A gene in the fruit fly D. melanogaster is found to affect neuronal function when mutated. A homologue of this gene is identified in mice (e.g. a gene likely descended from a last common ancester). Which of the following methods would it make most sense for a scientist to use to study the function of the gene in mice? Check all that apply. O CRISPR-Cas9 genome editing targeting the gene of interest followed by homologous recombination (HR) with a donor template O Reverse genetics O Whole genome sequencing OCRISPR-Cas9 genome editing targeting the gene of interest followed by nonhomologous end joining (NHEJ)

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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A gene in the fruit fly D. melanogaster is found to affect neuronal function when mutated. A homologue of this gene is identified in mice (e.g. a gene likely descended from a last common ancester). Which of the following methods would it make most sense for a scientist to use to study the function of the gene in mice? Check all that apply. O CRISPR-Cas9 genome editing targeting the gene of interest followed by homologous recombination (HR) with a donor template O Reverse genetics O Whole genome sequencing OCRISPR-Cas9 genome editing targeting the gene of interest followed by nonhomologous end joining (NHEJ) O Oligonucleotide-directed mutagenesis OForward genetics
Transcribed Image Text:A gene in the fruit fly D. melanogaster is found to affect neuronal function when mutated. A homologue of this gene is identified in mice (e.g. a gene likely descended from a last common ancester). Which of the following methods would it make most sense for a scientist to use to study the function of the gene in mice? Check all that apply. O CRISPR-Cas9 genome editing targeting the gene of interest followed by homologous recombination (HR) with a donor template O Reverse genetics O Whole genome sequencing OCRISPR-Cas9 genome editing targeting the gene of interest followed by nonhomologous end joining (NHEJ) O Oligonucleotide-directed mutagenesis OForward genetics
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