A disease in frogs which causes their tongue to fall out of their mouths is killing the frog population in LA County. You obtain a dead frog and isolate its gene Xf. When you sequence this mutated gene, you find that the last ‘G’ at the end of the first line of this sequence has been deleted (i.e. the G at position 86). In order to determine how this mutation changes the resulting polypeptide, write the mutated polypeptide sequence in the space below. What kind of mutation was produced? The mutated polypeptide sequence is What kind of mutation was produced?
A disease in frogs which causes their tongue to fall out of their mouths is killing the frog population in LA County. You obtain a dead frog and isolate its gene Xf. When you sequence this mutated gene, you find that the last ‘G’ at the end of the first line of this sequence has been deleted (i.e. the G at position 86). In order to determine how this mutation changes the resulting polypeptide, write the mutated polypeptide sequence in the space below. What kind of mutation was produced? The mutated polypeptide sequence is What kind of mutation was produced?
Chapter8: Forms Of Drugs And How They Act
Section: Chapter Questions
Problem 28RQ
Related questions
Question
a. The reading frame DNA sequence is:
b. The mRNA sequence is:
c. The polypeptide sequence is:
A disease in frogs which causes their tongue to fall out of their mouths is killing the frog population in LA County. You obtain a dead frog and isolate its gene Xf. When you sequence this mutated gene, you find that the last ‘G’ at the end of the first line of this sequence has been deleted (i.e. the G at position 86). In order to determine how this mutation changes the resulting polypeptide, write the mutated polypeptide sequence in the space below. What kind of mutation was produced?
The mutated polypeptide sequence is
What kind of mutation was produced?
![File: gvf11b11.y1
Machine: Cochise-1414-017
Matrix
Lane: 93
Primer: DT3730POP7{BDV3).mob
Comment: 1778D3
Spacing: 15.06
Signal: C: 1728 A: 3254 G: 2538 T: 2619
Bases: 903
Gel name:
Gel start date: 3 Jan 2004
Gel start time: 4:123
10
20
30
40
50
60
70
80
NNACTCA TCTGGTGGA TTC C TA TC CTG AC A AG TG ATGTG CAAA C TG G TAACTC TG AG GCAG A TAAC CA G GG CA AA AAG GTG TATAAG
120
130
150
90
TAAA ACA AAGCCTAACT TG GAAGAAAGAGAGAAA A AGT TCA G TT TTACACA TCT TTA TA TGAAGCAGA AG TC CG GA AA A TCA TT TA A AGAT
100
110
140
160
170
210
240
250
180
TAT TCTAT TA ATGTCCTGT TA TA TT TG T CATATTCA TA CAGT TG TCACAGTA TA T T TCAAAC CA AC TG TTTAAA A ACAA AC TG AAA TA AA
190
200
220
230
260
270
AAATTTAAA TACCCT TA TG TA AA ATAG GCT TC CCTGGTG GCTCAG GG GTAAA AA ACTCGCCCG C CA ACGCAGGAGATGTAGAT TTGATC CC T
280
290
300
310
320
330
340
350
360
370
380
390
400
410
420
430
440
GG GT TAG GA AGATCCCCTG GAGA AGGAAATGAAAAAC CACTCTAGTATTCTTGC CTG GG A A AT C CCATGGACAG AG GAGCGTGGAGG GC
450
TACAGTCCATGGGAGTCGCAAA AGAGT TG GACATG ACTAAACAACAACATATAAAATAACCT TACTCCATAATGTCAAACT TATGTCACAC
460
470
480
490
500
510
520
530
620
540
AAAATGCA A AGT TCT TACATCTATTA ACTTTTATGGT TA AATATAACCTAATGCACTGTTT TATACAGCAACAACTACTTTTT TATTT TAAA
550
560
570
580
590
600
610
630
650
660
720
TG GTGAAA AAT TAGTGA ACAGAGGGT CTCAGAGATGCTAAACT TATGACT TATAAT TAACAAGATGTTATAGTTCTAGACAT TT TTGATAT
640
670
680
690
700
710
Wan](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F4d62cc64-0378-4638-9893-20a25cf6ef2f%2F19518d37-d63f-4590-b422-b058245cf191%2F9osjwuq_processed.png&w=3840&q=75)
Transcribed Image Text:File: gvf11b11.y1
Machine: Cochise-1414-017
Matrix
Lane: 93
Primer: DT3730POP7{BDV3).mob
Comment: 1778D3
Spacing: 15.06
Signal: C: 1728 A: 3254 G: 2538 T: 2619
Bases: 903
Gel name:
Gel start date: 3 Jan 2004
Gel start time: 4:123
10
20
30
40
50
60
70
80
NNACTCA TCTGGTGGA TTC C TA TC CTG AC A AG TG ATGTG CAAA C TG G TAACTC TG AG GCAG A TAAC CA G GG CA AA AAG GTG TATAAG
120
130
150
90
TAAA ACA AAGCCTAACT TG GAAGAAAGAGAGAAA A AGT TCA G TT TTACACA TCT TTA TA TGAAGCAGA AG TC CG GA AA A TCA TT TA A AGAT
100
110
140
160
170
210
240
250
180
TAT TCTAT TA ATGTCCTGT TA TA TT TG T CATATTCA TA CAGT TG TCACAGTA TA T T TCAAAC CA AC TG TTTAAA A ACAA AC TG AAA TA AA
190
200
220
230
260
270
AAATTTAAA TACCCT TA TG TA AA ATAG GCT TC CCTGGTG GCTCAG GG GTAAA AA ACTCGCCCG C CA ACGCAGGAGATGTAGAT TTGATC CC T
280
290
300
310
320
330
340
350
360
370
380
390
400
410
420
430
440
GG GT TAG GA AGATCCCCTG GAGA AGGAAATGAAAAAC CACTCTAGTATTCTTGC CTG GG A A AT C CCATGGACAG AG GAGCGTGGAGG GC
450
TACAGTCCATGGGAGTCGCAAA AGAGT TG GACATG ACTAAACAACAACATATAAAATAACCT TACTCCATAATGTCAAACT TATGTCACAC
460
470
480
490
500
510
520
530
620
540
AAAATGCA A AGT TCT TACATCTATTA ACTTTTATGGT TA AATATAACCTAATGCACTGTTT TATACAGCAACAACTACTTTTT TATTT TAAA
550
560
570
580
590
600
610
630
650
660
720
TG GTGAAA AAT TAGTGA ACAGAGGGT CTCAGAGATGCTAAACT TATGACT TATAAT TAACAAGATGTTATAGTTCTAGACAT TT TTGATAT
640
670
680
690
700
710
Wan
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