7. The following diagram shows the two chromosomes in an individual heterozygous for an inversion, as well as genes A through F. The inversion is indicated by the thick line. What will happen if a recombination occurs in the region between genes A and B? a. A dicentric chromosome will be produced b. The telomeres of each chromosome will be lost c. The telomeres of each chromosome will be duplicated d. An acentric chromosome will be produced e. A normal recombination event

7. The following diagram shows the two chromosomes in an individual heterozygous for an inversion, as well as genes A through F. The inversion is indicated by the thick line. What will happen if a recombination occurs in the region between genes A and B? a. A dicentric chromosome will be produced b. The telomeres of each chromosome will be lost c. The telomeres of each chromosome will be duplicated d. An acentric chromosome will be produced e. A normal recombination event

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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6). To investigate the genetic control of locomotive behavior in the diploid nematode, Caenorhabditis elegans, eight "wiggly" mutants were isolated, which wiggle in an uncoordinated way rather than smoothly gliding. These eight mutants were crossed together in all possible pairwise combinations, yielding the results summarized in the table above (+ means that all the progeny were wild type, and m means that all the progeny showed the wiggly mutant phenotype). Organize the eight mutations into con lementation groups, each consisting of a group of mutations affecting the same gene. 1 2 3 4 5 6 7 8 1 E N+E 2 3+1 m + m 4 5 + m m E+ + + EE 6 ++E E+ +EE m m + + + + + + + + + m 7 8 ++4 ∞+E +E m m ++ E
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7. The following diagram shows 2 pairs of autosomal chromosomes in a karyotype of a biological woman. Based on the karyotype, a genetic counsellor determined that there is evidence that a translocation occurred between two non-homologous chromosomes. The other 21 pairs of chromosomes are NOT shown in this diagram. Assume no chromosomal aberrations occurred in the other chromosomes. As a student-researcher, the genetic counsellor asks you if you can determine whether the translocation occurred in a somatic cell, germ-line cell, or whether this can even be determined from the figure? Provide an answer and the reasoning for your answer. D
What kind of chromosome rearrangement (shown as ?) is represented below? a. insertion b. Pericentric inversion c. Robersonian translocation d. Paracentric inversion e. balanced translocation
The normal sequence of nine genes on a certainDrosophila chromosome is 123 • 456789, where the dotrepresents the centromere. Some fruit flies were foundto have aberrant chromosomes with the followingstructures:a. 123 • 476589 c. 1654 • 32789b. 123 • 46789 d. 123 • 4566789Name each type of chromosomal rearrangement, anddraw diagrams to show how each would synapse withthe normal chromosome.
36 The diagram below represents a cell containing a pair of chromosomes at metaphase I of meiosis. The individual is a heterozygote for two tightly linked genes, gene A and gene B. a b A B If a crossing over event occurred between alleles A and B in the cell shown above, what are the genotypes of the two possible recombinant gametes? Select one alternative: O aA bB O AB аB Ab O AB ab
please answer with thorough explanation
1. In the simple picture below we are focusing on the chromosomes. Notice that the chromosomes are condensed and the nuclear membrane and spindles are not shown. a. Please label the following and indicate with arrow(s): sister chromatids, a pair of homologous chromosomes, a centromere. b. Label the part of diagram that indicates a double helical molecule of DNA and highlight it with a thick line. c. How many molecules of DNA are shown in this picture? d. Is this cell haploid or diploid (circle one). How do you know? e. Below the diagram, indicate the ploidy (number of sets of information) and the number of chromosomes X n= ploidy (# of sets of information) X X M # of 2. The circle below represents the cell cycle. chromosomes a. Write the phases (G1, G2, M and S) in the appropriate sections. b. Which phase results in identical sister chromatids? c. In which phase do sister chromatids separate?
1.Describe the rearrangement in chromosomes A-C. indicate the specific markers genes flanking the crossover/breakage points (e.g., a translocation with breakpoints between markers X and Z). 2.Chromosome rearrangements can be caused by crossing over between repetitive DNA sequences. Draw a picture similar to Figure showing how crossovers between repetitive sequences could have produced chromosome rearrangement A. indicate the location and orientation of the repetitive DNA segments relative to the marker genes.
5. In German Shepherd dogs, hair length and hip dyslpasia are determined by two different genes located on different chromosomes. In answering the following questions, use the letters D and d for fur length and H and h for hip dysplasia. Max, a long-haired dog with no hip dysplasia, was bred with Rin, a short-haired dog that was later found to have hip dysplasia. All of their children had long hair and hip dysplasia. a. Give the genotypes of the following: Мах Rin Their children (the F,) Buddy is a German Shepherd dog with short hair and was heterozygous for having hip dysplasia. b. What is Buddy's genotype? c. Give the genotypes of all of the gametes Buddy could produce.
11. The discovery of chromosome banding in eukaryotes has greatly improved our ability to distinguish various cytogenetic events. Particularly useful are “banding" polymorphisms because the "morphs" can be used as chromosome markers. (These morphs are forms of chromosome that are cytologically distinguishable by virtue of minor variations in band size, position, etc). Let's consider chromosome 21 in humans. Assume that one set of parents are: 21°21 (female) x 21°21ª (male), where a, b, c and d represent "morphs" of a polymorphism for this chromosome. In each case: State the genetic term for the condition (if possible), diagram the event(s) that gave rise to the condition, and state in which individual the event(s) took place. d. 42A + 2121°21° + XX dad MII Interphase [show condensed]: Interphase [show condensed]: Diagram meiosis for After DNA replication: After DNA replication: chromosome 21 in Mom (left) and Dad (right) After Meiosis I: After Meiosis I: Gametes: Gametes: 21 21 21°