6. The famous geneticist, T.H. Morgan, carried out a series of experiments on linkage mapping in Drosophila. He constructed a series of three-point testcrosses for his mapping studies. What is a three-point testcross (Diagram the genotypes of the parents involved in such a cross)? How many F1 progeny classes are possible from such a cross (show your calculation for your answer)? 1_11_2021 In one such cross, Morgan examined the linkage of three genes v (vermillion eye), cv (crossveinless wings), and ct (cut wing margin). These three are the mutant phenotypes, the wildtype being red eye, crossvein and normal wing margin. From a three-point testcross he obtained the following progeny: + + + AA + > > V + V CV CV +Q CV ct U+ ++++ + ct ct - 580 - 45 - 5 94 CV ct What is the genetic map of these three loci? - 592 40 3 89 3
6. The famous geneticist, T.H. Morgan, carried out a series of experiments on linkage mapping in Drosophila. He constructed a series of three-point testcrosses for his mapping studies. What is a three-point testcross (Diagram the genotypes of the parents involved in such a cross)? How many F1 progeny classes are possible from such a cross (show your calculation for your answer)? 1_11_2021 In one such cross, Morgan examined the linkage of three genes v (vermillion eye), cv (crossveinless wings), and ct (cut wing margin). These three are the mutant phenotypes, the wildtype being red eye, crossvein and normal wing margin. From a three-point testcross he obtained the following progeny: + + + AA + > > V + V CV CV +Q CV ct U+ ++++ + ct ct - 580 - 45 - 5 94 CV ct What is the genetic map of these three loci? - 592 40 3 89 3
Human Anatomy & Physiology (11th Edition)
11th Edition
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Chapter1: The Human Body: An Orientation
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Transcribed Image Text:Certainly! Here's the transcription and explanation for an educational context:
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**Genetic Linkage Study by T.H. Morgan**
**6. Experimental Background:**
The renowned geneticist, T.H. Morgan, conducted a series of experiments on linkage mapping in *Drosophila*. He developed a series of three-point testcrosses for his mapping studies.
**Understanding the Three-Point Testcross:**
- **Question:** What is a three-point testcross? (Diagram the genotypes of the parents involved in such a cross.)
- **Calculation Task:** How many F1 progeny classes are possible from such a cross? (Provide your calculations for your answer.)
**Detailed Experiment: 1_11_2021**
In one such experiment, Morgan analyzed the genetic linkage of three genes:
- **v (vermillion eye)**
- **cv (crossveinless wings)**
- **ct (cut wing margin)**
These three are mutational phenotypes, with the wildtype exhibiting red eye, crossvein, and normal wing margin. From a three-point testcross, Morgan observed the following progeny distribution:
- **v + +**: 580
- **v cv +**: 45
- **v + ct**: 5
- **+ cv +**: 94
- **+ + ct**: 3
- **+ cv ct**: 592
- **v cv ct**: 40
- **+ + +**: 89
**Analysis Question:**
- **What is the genetic map of these three loci?**
This setup allows researchers to map the genetic distances between the loci by analyzing the distribution of phenotypes among the progeny.
**Diagrams and Graphs:**
- There are no diagrams or graphs included in the provided content.
- To represent the testcross visually, one could draw a genetic linkage map showing the relative positions and distances between the three loci based on recombination frequencies.
This educational exercise exemplifies a foundational method used for understanding gene linkage and mapping in genetics.
---
This transcription maintains the educational integrity and context necessary for understanding T.H. Morgan's experiment.
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