7. Explain what would happen to red blood cells placed in each of the following solutions. Remember isotonic solutions contain 0.9% (w/v) NaCl. a. 0.05 % (w/v) NaCl b. 0.90 % (w/v) NaCl c. 2.0% (w/v) NaCl d. distilled water e. 10 % (w/v) NaCl
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- 1. compute for patient B result of his chloride analysis with the following data using mg/dL unit factor: 355/ mg/dL , Absorbance sample = 0.2148, Absorbance standard = 0.3017 a. 24.8 mg/L b. 25.27 mg/dL c. 2.7119 mmol/L d. 252.7 mg/dL 2. an adult patient suffering from debilitation is supected of calcium deficiency. His doctor requested for calcium anaylusis with the following data gathered standard known value is B: Absorabance is 0.2876. sample absorbance is 0.4291 compute for the calcium in mmol/L a. 53.6mmol/L b. 5.36 mmol/L c. 11.9 mmol/L d. 119mmol/L 3. calculate the value of sodium where the PREC solution has diclored. data gathered are the following: Absorbance of Reagent Blank = 0.3124 Absorbance of sample = 0.114, Absorbance of standard = 0.275 value is 150mmol/L a. 108.2 mmol/L b. 170.4 mmol/L c. 795.72 mmol/L d. 79.5 mmol/L7. · In the space provided, sketch a titration curve (pH vs H+ ions dissociated) of a phosphate buffer shown below. The pKa of H2PO4 is 7.0. H,PO, НРО, + 9. 8. 7 pH 3 1.0 0.5 H+ dissociated --> b. What is the effective buffering range of this acid? At what pH will you have 25% of the buffer in the form of H2PO4? с.Discuss why saline in IV bags has a 0.9% NaCl concentration.
- a. calculate the volume of 0.1 M H2PO4– required to prepare 100 mL of your assigned buffer. b. calculate the volume of 0.1 M HPO42– required to prepare 100 mL of your assigned buffer. 1. Assigned pH Value ___6.90_________ 2. pKa Value of Assigned Buffer ___7.20_________ 3. Ratio 0.50111. A hospital pharmacy has available 2-mL prefilled syringes containing 80 mg of tobramycinand 1.5-mL prefilled syringes containing 60 mg of tobramycin. The syringes are calibratedin 0.25-mL units. Explain how you would prepare a medication order calling for 110 mgof tobramycin to be added to 100 mL of D5W for intravenous infusion. 2. A physician prescribes a 5-mcg/kg/min IV drip of dopamine for a 175-lb. patient, and thepharmacist adds an ampul of dopamine (200 mg/5 mL) to a 250-mL bottle of D5W. Whatdrip rate should be run, in drops per minute, using a minidrip set that delivers 60 drops/mL? 3. A physician orders an intravenous solution to contain 10,000 units of heparin in 1 literof 5% w/v dextrose solution to be infused at such a rate that the patient will receive500units per hour. If the intravenous set delivers 10 drops/mL, how many drops per minuteshould be infused to deliver the desired dose?5. Using this formula Cu = Au X Cstd. Astd Where: C = concentration A = absorbance U = unknown/sample STD = standard Compute for the glucose concentration of the patient's sample. Absorbance of the standard = 0.075; Concentration of the standard = 10.54 Absorbance = 0.83 Convert you answer to mmol/L or S.I. using the conversion factor for glucose which is 0.055 Please show your computation.
- When 100 mg of a drug is administered as an IV bolus dose, the plasma concentrations (ug/mL) observed over time (hr) can be described by the following equation: C = 3.6e-0.105t C= 3-6e AUC 36 6 -0.105t 5. Calculate AUC(0-0) 0-105 = 34.28 6. What is the volume of distribution? Dose 100 VD= Co 3-6 7. Calculate the clearance of this drug. CI = KXVD CI = 0•105 x 27-8 %3D %3D Cl=2.9 8. What IV dose would be required to produce an initial plasma concentration of 10 ug/mL?1. The Henderson-Hasselbalch equation for the blood bicarbonate system is: pH = 6.1 + log b. Calculate the ratio for a blood pH of 8.8. c. Is this patient experiencing acidosis or alkalosis? Why? d. What can the body do to restore normal blood pH levels? Why is the body at a pH outside of the prime buffering zone of the bicarbonate system2. A 70-kg male subject was given 150 mg of a drug by IV injection. Blood samples were removed and assayed for intact drug. Calculate the slopes and intercepts of the three phases of the plasma level-time plot from the results tabulated below. Give the equation for the curve. Download (.pdf)|Print Time (hours) 0.17 0.33 0.50 0.67 1.00 1.50 2.00 C(μg/mL) 36.2 34.0 27.0 23.0 20.8 17.8 16.5 Time (hours) 3.0 4.0 6.0 7.0 18.0 23.0 C(ug/mL) 13.9 12.0 8.7 7.7 3.2 2.4
- Hi I needed help with this question: The half-life of pseudoephedrine (Sudafed) is 4 hours. If Joe took a 40mg dose at 4pm, and another 40mg dose at 8pm, what concentration is present in Joe’s blood at Midnight?4. Order: Start Pitocin drip, 10 units in NS 1000 mL, at 12 mL/hr Available: oxytocin 10 units/mL a. What is the concentration of the solution? b. What is the dosage concentration per hour? c. What is the volume per min?An IV infusion is to contain 40 mEq of potassium ion and 10 mEq of sodium ion in 500 mL of D5W.Using a 20% w/v potassium chloride injection (MW 74.5, valence of 1) and 0.45% sodium chlorideinjection (MW 58.5, valence of 1), how many milliliters of each should be added to the 500mL bag ofD5W to supply the required ions?