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7 Monomeric protein A reacts with an excess of 2-mercaptoethanol and gives protein B. The latter gives, under the influence of excess 2-iodoxic acid, the protein derivative C. H2N-(AA)-Cys-(AA)-Lys-(AA)-Cys-(AA)-COOH HOOCCH₂S SCH2COOH C a) Determine the primary structure of protein A. b) Explain whether derivative C can give by simple oxidation the original protein A. Explanation: Assume that the numbers (a-d) and type of amino acids (AA) are known.

7 Monomeric protein A reacts with an excess of 2-mercaptoethanol and gives protein B. The latter gives, under the influence of excess 2-iodoxic acid, the protein derivative C. H2N-(AA)-Cys-(AA)-Lys-(AA)-Cys-(AA)-COOH HOOCCH₂S SCH2COOH C a) Determine the primary structure of protein A. b) Explain whether derivative C can give by simple oxidation the original protein A. Explanation: Assume that the numbers (a-d) and type of amino acids (AA) are known.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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7 Monomeric protein A reacts with an excess of 2-mercaptoethanol and gives protein B. The latter gives, under the influence of excess 2-iodoxic acid, the protein derivative C. H2N-(AA)-Cys-(AA)-Lys-(AA)-Cys-(AA)-COOH HOOCCH₂S SCH2COOH C a) Determine the primary structure of protein A. b) Explain whether derivative C can give by simple oxidation the original protein A. Explanation: Assume that the numbers (a-d) and type of amino acids (AA) are known.
Transcribed Image Text:7 Monomeric protein A reacts with an excess of 2-mercaptoethanol and gives protein B. The latter gives, under the influence of excess 2-iodoxic acid, the protein derivative C. H2N-(AA)-Cys-(AA)-Lys-(AA)-Cys-(AA)-COOH HOOCCH₂S SCH2COOH C a) Determine the primary structure of protein A. b) Explain whether derivative C can give by simple oxidation the original protein A. Explanation: Assume that the numbers (a-d) and type of amino acids (AA) are known.
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