A. Briefly discuss the four levels of structure in proteins.

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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3.
A. Briefly discuss the four levels of structure in proteins.
Knowing that the 3-dimensional shape of a protein is important to its function, discuss on a qualitative basis whether the
changes below will likely alter the function of a protein, justifying your answer with why or why not.
B. What would happen to a protein's functionality if a serine residue were replaced with threonine?
C. What would happen if serine were replaced with leucine?
D. What would happen if serine were replaced with cysteine?
E. What would happen if aspartic acid were replaced with tryptophan in the part of the protein (an enzyme) that serves as
an active site to catalyze a reaction?
F. What would happen if aspartic acid were replaced with tryptophan in a non-active site?
Transcribed Image Text:3. A. Briefly discuss the four levels of structure in proteins. Knowing that the 3-dimensional shape of a protein is important to its function, discuss on a qualitative basis whether the changes below will likely alter the function of a protein, justifying your answer with why or why not. B. What would happen to a protein's functionality if a serine residue were replaced with threonine? C. What would happen if serine were replaced with leucine? D. What would happen if serine were replaced with cysteine? E. What would happen if aspartic acid were replaced with tryptophan in the part of the protein (an enzyme) that serves as an active site to catalyze a reaction? F. What would happen if aspartic acid were replaced with tryptophan in a non-active site?
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