6. Which of the following statements concerning the BLOSUM62 substitution matrix is correct? a. Ala is aligned with Arg more often than expected by chance. b.Ala is never substituted by Cys. c. Tryptophan is substituted less frequently than any other amino acid.

Q: 63. A student studying mutations found her amino acid chain was…

A: Genetic information is carried by genes to make proteins .  Process includes:-  I ) Transcription II…

Q: 18. Chaperones are frequently associated with polypeptides as they are being synthesized from the…

A: Chaperons are proteins that are primarily concerned with protein folding. It prevents the…

Q: 2) Myoclonal epilepsy and ragged red fiber disease (MERRF) is a human condition named for the ragged…

A: Mitochondrial tRNA in humans has gained interest due to the discovery of associations between point…

Q: A peptide was cleaved into two smaller peptides with cyanogen bromide (CNBr) and into two different…

A: The given peptide sequences are: CNBr 1: Gly-Thr-Lys-Ala-Glu CNBr 2: Ser-Met Tryp 1:…

Q: Take a look at the multiple-sequence alignment shown ofthe globin polypeptides, focusing on amino…

A: BLAST is a local alignment search tool that is used to obtain the nucleotide or protein sequences of…

Q: 34. Dolichol phosphate  a. assists chaperons in protein folding  b. recognizes the ER targeting…

A: The correct answer to the question is: d. is a lipid carrier for oligosaccharides in the ER.

Q: 1. H₂N a. Draw the peptide sequence, including stereochemistry (wedges and dashes) for Glu-Cys- Gly.…

A: Stereochemistry refers to the illustration of the arrangement or connectivity of atoms to a chiral…

Q: 4. You are to choose the members of an expedition that will climb several high mour Each applicant…

A: Hemoglobin abnormalities are referred to as the type of blood disorders that have a major impact on…

Q: Describe the distinct SH domains and their binding specificities. How are SH domains in regulating…

A: * specific protein-protein interactions can be mediated by the binding peptides to small modular…

Q: 6. Please describe the events that may result in a mature protein not having methionine as the…

A: DNA is the carrier for genetic information in almost all organisms except certain RNA viruses. DNA…

Q: 2) Myoclonal epilepsy and ragged red fiber disease (MERRF) is a human condition named for the ragged…

A: Myoclonic epilepsy:It is related to a family of epilepsies which are present along with myoclonus.…

Q: In a folded protein, Glu116 is close in three-dimensional space to Lys224. The pKa of the carboxylic…

A: pKa is the pH at which a weak acid is 50% dissociated. Alternatively, pKa = -log Ka. In acid-base…

Q: List the amino acid sequence of the protein coded for.…

A: The translation is the process of synthesis of amino acids from the mRNA. During the translation…

Q: 3). Consider the four mutations (i-iv) described below: i. One of the mutations causing cystic…

A: A mutation is a permanent change in the DNA sequence of an organism's genome. Mutations can occur…

Q: 1. Explain why the primary structure sequence -Lys-Leu-Trp-Asp- may promote a-helix formation while…

A: The formation of α helix is occurred due to attachment of H of N of Cα of first (n) amino acid to…

Q: Please describe the events that may result in a mature protein not having methionine as the…

A: Translation process of formation of a sequence of amino acid using messenger RNA as a template.

Q: A21. Two single-base substitutions in the trpA gene of E.coli both affected amino acid number 234.…

A: Missense mutation defines the alteration of genetic code/codon via the single base pair…

Q: AAG a. What is indicated by label (2) in the figure above? b. What is indicated by label (3) in the…

A: “Since you have posted a question with multiple sub-parts, we will solve first three subparts for…

Q: Distinguish between:- a. Glycoproteins and Proteoglycans. b. SIRNA and MIRNA

A: Glycoconjugates are carbohydrates that have been covalently bonded to an amino acid,…

Q: 1. Using the data available describe the phenotype that you observe when each of these three genes…

A: The question is related to the use of RNA interference (RNAi) to study the function of specific…

Q: 3. Which of the following post-translational modifications will alter amino acid charge? a)…

A: Post-translational modifications (PTMs) are crucial mechanisms in the regulation of proteins'…

Q: The figure above shows some of the more common modifications, such as phosphorylation (1),…

A: Phosphorylation- Protein phosphorylation occurs in post-translational modification. Here phosphate…

Q: 33. Band 3 protein exists as a 95-kDa multipass membrane protein that functions as the primary anion…

A: Given,          Band 3 protein ,a protein which is essential for RBC membrane support and also acts…

Q: 1. How many different tripeptides are possible? How many carboxyl terminals of polypeptide chains…

A: Tripeptides are composed of three amino acids. There are 20 naturally occurring  amino acids . A…

Q: A lysine is on the surface of a protein near an arginine, how does this alter pKa of lysine

A: The pKa of an amino acid's side chain determines whether it is protonated (+) or deprotonated (-)…

Q: Mature human insulin is synthesized from a single Gene but contains two polypeptide chains (A and B)…

A: In the control of human metabolism, insulin is crucial. The -cells in the Islets of Langerhans…

Q: 1. What genetic changes can occur in bacteria to make them resistant to triclosan? 2. How could the…

A: Since you have posted multiple questions, we will provide the solution only to the first question as…

Q: Distinguish between:- a. Glycoproteins and Proteoglycans. b. SIRNA and MiRNA

A: Glycoproteins Proteoglycans Glycoproteins are a class of conjugated proteins, with a prosthetic…

Q: (a) dues in the polypeptide. Place the label or an arrow on the Ca atom of both residues. Label the…

A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…

Q: Iron-uptake protein IupA is a human 302-aa, N-glycosylated, heterodimeric protein of considerable…

A: Escherichia coli is one of the organisms of choice for the production of recombinant proteins. Its…

Q: 1. With reference to the figure, discuss the results of the Western Blotting experiments, what they…

A: This is the technique that is used to analyze various proteins from the mixture extracted from…

Q: 1. What is the length in AA’s of the LilP protein? Assume fMet is NOT CLEAVED. 2. Write out the…

A: Introduction  DNA (Deoxyribonucleic acid) sequence is the order of nucleotide bases (adenine,…

Q: 1. "Interferons (IFNs)‐α and ‐β are expressed in response to a virus infection and are released from…

A: Interferons inactivates protein synthesis in cells to block the viral replication.

Q: 2. The diagram to the right shows the change in the structure of the C-terminal portion of each of…

A: Therefore, the final answer is: (a) Without the His146 residue, CPA-treated hemoglobin would have a…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.