A lysine is on the surface of a protein near an arginine, how does this alter pKa of lysine

Q: You are studying a eukaryotic protein PKK in the lab. You fuse the DNA encoding GFP (green…

A: Proteins synthesized through translation process is directed to specific locations in the cells.…

Q: A protein substrate is known to be multi-monoubiquitinated. The control lane "C" in the SDS-PAGE gel…

A: The proteins are separated on the basis of their molecular weight by the technique known as Sodium…

Q: What are the primary structures of TATA-binding protein (for ex. letter amino acids),  What are the…

A: TATA-binding proteins (TBP) bind to Sequences on DNA called TATA boxes. TBP is a general…

Q: Which of the following is the LEAST likely ER signal sequence? All sequences are written with their…

A: ER signal sequences are amino acid sequences in proteins that direct protein transport to the…

Q: Two proteins have exactly the same amino acid sequence. Protein A is able to bind with high affinity…

A: Only certain substances can diffuse through the cell membrane as the cell membrane is selectively…

Q: Both Pfizer and Moderna MRNA vaccines use the lipid DSPC (see figure below) in constructing the…

A: The vaccines are the specific molecules that helps us developing passive immunity. Vaccination helps…

Q: A different Fab fragment binds to lysozyme with a dissociation constant of Kd=10-6 M. A 1 nM (10-9…

A: Consider the following reaction: where P is the protein, L is the ligand and k1 and k2 are rate…

Q: How can the two tight junction strands remain even after the disappearance of claudin-4 caused due…

A: Tight junctions are the structures present between some animal cells to prevent the leakage of…

Q: antisense DNA strand?

A: Sense strand: This is the segment of double stranded DNA which runs from 5' to 3' direction. This…

Q: In the case of the bacterial two-Na+/one-leucine symporter, what is the key distinguishing feature…

A: Bacterial two-Na+/ one-leucine symporter consists of 12 membrane-spanning α helices. The leucine…

Q: by namlng the amlno aclds from the N-terminal to the C- terminal. Use the long name, the 3-letter…

A: Bradykinin is a nonapeptide that means it contains 9 amino acid. At low pH, a peptide remain full…

Q: Some years ago, it was suggested that the function of the poly(A) tail on a eukaryotic message may…

A: Polyadenylation is the one of the steps of the RNA processing method or post-transcriptional…

Q: Members of the integrin family are the major cell surface receptors for many ECM proteins such as…

A: Integrins are a family of αβ heterodimers. Integrins are cellular adhesion receptor molecules that…

Q: Sort the following events to reflect the order in which they should occur during vesicle docking…

A: Answer correct option (b) 3124 Vesicle have bounded Rab-GTP which interacts with Rab effector…

Q: What is mechanism of intein splicing to join P1 and P2 ? Which steps are reversible and which ones…

A: DNA is the genetic carrier that carries genetic information from one generation to another. DNA is…

Q: What amino acid residues are phosphorylated on the intracellular domain of a VEGFR? Glutamic Acid…

A: VEGFR: VEGF receptors are vascular endothelial growth factor receptors (VEGF). VEGFR is divided into…

Q: Consider, for example, that a particular serine residue is phosphorylated to activate the protein.…

A: Phosphorylation can either activate or deactivate a protein. Phosphomimetics replaces amino acids in…

Q: Where will the amino (NH2) terminus of the protein be located (cytosol vs. ER lumen) if the “start”…

A: The endoplasmic reticulum is a cell organelle which is an extension of the nuclear envelope. Its…

Q: A new protein is discovered that contains a pleckstrin homology domain. Which of the following…

A: Pleckstrin homology domain is a domain in protein and is made up of nearly 120 amino acids. It is…

Q: N' C' = Polypeptide X d a b = SRP 5'- = translocator e Which region(s) of polypeptide X would bind…

A: Ribosomes refer to the site where the protein synthesis takes place. It comprises rRNA and protein.…

Q: The following sequence is a portion of the N-terminus of the ACE2 receptor.  The secondary structure…

A: Each amino acid has a different property.

Q: Each type of molecule listed below is recognized by a specific class of nuclear import receptor…

A: Importin and exportin refer to the nuclear transport receptors that are responsible for the…

Q: Explain the way in which the glycophorin proteins having hydrophobic transmembrane domains associate…

A: The red blood cell's plasma membrane contains tiny, single-pass transmembrane glycoproteins called…

Q: The PAM1 matrix penalizes mismatching amino acids more than higher numbered PAM matrices. Explain…

A: PAM (POINT ACCEPTED MATRIX) indicates the probability of a mutation of an amino acid in a given…

Q: There was a study done (Isabel, et al.) on structural analysis of SARS-CoV-2 spike protein. The…

A: Hydrophobic groups are non-polar. These have a very low affinity with the polar groups. However,…

Q: Identify the various secondary structures in the β1 immunoglobulin-binding domain of protein G…

A: The secondary structure of the protein predominantly contains the alpha-helix and the beta-sheet. In…

Q: The peptide Leu-Cys-Arg-Ser-Gln-Met is subjected to Edman degradation. After the first cycle of this…

A: Peptide refers to a chain of amino acids which contains about 2 to 50 amino acids. A peptide chain…

Q: Given the following coding strand of DNA: 3' – TACCGAGTACTGACT – 5', the mRNA that will transcribed…

A: The method of constructing an RNA copy of a genetic sequence is known as transcription. The copy,…

Q: What amino acid would a tRNA with anticodon CUA carry? Enter the 3 letter code only [A]. [e.g. Met…

A: tRNA stands for the transfer RNA and it has L- shaped structure . Transfer RNA acts as an adopter…

Q: Describe the function of the Bicoid protein. Explain how its ability to exert its effects in a…

A: The proteins are the biomolecules found in all organisms.

Q: You are studying how your Lys-Val-Thr tripep de interacts with another pep de, which places an Asp…

A: Eventhough all ionizable groups have their characteristic pKa value, the pKa value of an ionizable…

Q: What is Adenine state its function.

A:

Q: pH @1 of Cys-His-Glu-Met-Ile-Ser-Thr-Arg-Tyr

A: Peptides are organic compounds made up of amino acids connected by peptide bonds. The specific…

Q: Transport of histidine into a bacterial cell was measured at several different histidine…

A: The kinetics of transport of a molecule via a carrier protein and a protein channel differ from each…

Q: why leucines are crucial part of GCN4 protein?

A: GCN4 is a protein that is usually known to be the controller of the gene expression in about one…