A lysine is burined inside a protein surrounded by hydrophobic resiudes, how does this affect the pKa of lysine?

Q: A mutation of Lysine to Alanine in the middle of TM1 has been associated with increased GPCR…

A: The lipid bilayer is a thin polar membrane. It is made up of two layers of lipid molecules. The…

Q: protein via transmembrane protein translocation:

A: Free ribosome : These ribosomes are located in the cytosol and are able to move throughout the cell…

Q: Why do alpha and beta tubulin monomers differ in sequence by 60%?

A: Tubulin is the protein filament, which polymerizes to form microtubules. These microtubules perform…

Q: What type of protein does FOG2 produce?

A: FOG 2 protein is coded by ZFPM 2. It is a family of transcription factors genes.

Q: Explain the binding problem.

A: The brain is one of the organs of the central nervous system, along with the spinal cord. It is…

Q: Pleasseee explain I’m confused…….

A: The charges of a peptide at different pH values depend on the ionization states of its amino acid…

Q: In TLC, why are the colors of the peaks for each amino acid are different depending on the types of…

A: TLC stands for Thin Layer Chromatography. It is a refined technique that is used for isolating or…

Q: Members of the integrin family are the major cell surface receptors for many ECM proteins such as…

A: Integrins are a family of αβ heterodimers. Integrins are cellular adhesion receptor molecules that…

Q: Discuss the general structure of the carrier proteins within our cells. Describe how their structure…

A: Integral membrane proteins called carrier proteins make it easier for molecules to penetrate cell…

Q: What amino acid residues are phosphorylated on the intracellular domain of a VEGFR? Glutamic Acid…

A: VEGFR: VEGF receptors are vascular endothelial growth factor receptors (VEGF). VEGFR is divided into…

Q: Which of the following sequences is most likely to represent a beta-sheet portion of a protein? O…

A: The β-sheet is a secondary structure motif of the protein structures. it is formed by the β-strands…

Q: For each of the following, describe the path the protein takes to its final destination in the cell.…

A: Abstract The seven-transmembrane protein, Smoothened (SMO), has shown to be critical for the…

Q: Where will the amino (NH2) terminus of the protein be located (cytosol vs. ER lumen) if the “start”…

A: The endoplasmic reticulum is a cell organelle which is an extension of the nuclear envelope. Its…

Q: A new protein is discovered that contains a pleckstrin homology domain. Which of the following…

A: Pleckstrin homology domain is a domain in protein and is made up of nearly 120 amino acids. It is…

Q: Polypeptides which are normally synthesized in the endoplasmic reticulum are about 20 amino acids…

A: Proteins are synthesized by the ribosomes present on the endoplasmic reticulum, thus they are known…

Q: The SARS-CoV-2 spike protein is heavily glycosylated. What are some of the monosaccharides found in…

A: The spike (S) protein of SARS-CoV-2 mediates the virus binding to the human cells via its…

Q: Melanosomes are specialized lysosomes that storepigments for eventual release by exocytosis. Various…

A: Introduction Melanosomes are organelles that produce and store melanin, a common biological pigment…

Q: Explain how both alpha helices and beta sheets can be used by proteins that cross membranes. Also…

A: Biological membrane is made up of phospholipids, proteins and carbohydrates. Membrane proteins are…

Q: Describe how the two (or more) binding events and structural change relates to the overall function…

A: * Proteins are made by linkage of amino acids together with each protein having a characteristic and…

Q: A lysine is on the surface of a protein near an arginine, how does this alter pKa of lysine

A: The pKa of an amino acid's side chain determines whether it is protonated (+) or deprotonated (-)…

Q: What types of amino acids are the least likely to be found in the center of a transmembrane protein?…

A: Biomolecules are organic molecules present in living organisms. Proteins are one of the major…

Q: Amino acids at the interaction site ( F,I and L) and its G protein partner (P, L, Y) are very…

A: GPCRs are also known by the name of G Protein Coupled Receptors. These are integral membrane…

Q: Erk and P-Erk live in two different locations within the cell even though they are just two…

A: * Mitogen activated protein kinase also called as  MAPK and  p42MAPK, and ERK2 * It is an enzyme…

Q: How many amino acids long is a zinc finger domain? What four conserved residues are contained in the…

A: Zinc finger are structural protein motif that has Zn ion in a coordinated bond to form a stable…

Q: Estimate the number of amino acid residues in each of the two helices of a segment of the…

A: The structural configuration of alpha-keratin proteins, a class of fibrous structural protein…

Q: What amino acid would a tRNA with anticodon CUA carry? Enter the 3 letter code only [A]. [e.g. Met…

A: tRNA stands for the transfer RNA and it has L- shaped structure . Transfer RNA acts as an adopter…

Scientific Notation

We have to deal with quantities that are extremely large or very small. For example- I may have 6,500,000,000 red blood cells, or the diameter of an iron atom is 0.000000011 inches. Numbers with many zeros can be inexpedient to work with, so scientists use scientific notation. It represents very large numbers or very small numbers in a simple form. We know that whole numbers can be extended to infinity, but we cannot write such large numbers on paper. Numbers that present in millions of places after the decimal point need to be represented simply. Thus, it is difficult to represent a few numbers in their extended form. Therefore, we use scientific notation.