4. You are to choose the members of an expedition that will climb several high mountains.Each applicant for one of the positions is a heterozygote for an abnormal hemoglobin:Person A: Hb Albany: a methionine has been substituted for Lys 82 in the B-subunit.Person B: Hb Cowtown: a leucine has been substituted for His 146 in the B-subunit.Person C: Hb Flagstaff: an isoleucine has been substituted for Val 1 in the B-subunit. and the KİNG exercises. Assuming that each of these candidates is equal in ability at lowaltitude, which one would you choose for the expedition? To answer this question, determinehow the substituted amino acid affects the structure and function of each abnormalhemoglobin, and describe the physiological effect. Focus on the stabilization of the T versusR state of hemoglobin, and the consequent physiological changes that might occur at highaltitude. Keep your answers brief.Person APerson BPerson C

Hemoglobin abnormalities are referred to as the type of blood disorders that have a major impact on…

Answered: 4. You are to choose the members of an…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

III. LAB REPORT You inherited your blood type from your parents. Your blood type is based on antigens found on your red blood cells named A or B and antibodies found in your plasma called a or b. See Table 1 for the antigen-antibody make-up of different blood types. Table 1 Blood type Antigens Antibodies A A b B B a AB A and B neither a nor b O neither A nor B both a and b A. When would clumping (or agglutination occur?
1 J are a broad category of small protein mediators that are important in the immune system and have an effect on migration of various cell types. Cutelines A
18. Your patient, Sally Sue who has AB- blood, receives blood from her older sister (Ruby, who's AB+). Afterwards, she has a cytotoxic reaction. Which of the following was the initial cause of the reaction? a. Sally Sue's blood type was actually AB+ b. Sally Sue had previously received AB+ blood c. Ruby's blood type was actually AB- d. Sally Sue had previously received A- blood e. Sally Sue had previously received B- blood 19. The indirect reason for the appearance of skin lesions due to a Type IV hypersensitivity is a. Tc cells b. IgE c. Mast cells d. perforin e. IgG || 5/12
4 and 5 thank you so much!
11. Why do SARS-CoV-2 virus as it spreads around the world? you think it would be important for epidemiologists to track minor genomic changes in the B U TI- e X2 x2 Write your answer...
7. Guanidinium group is associated with: a. Tyrosine b. Arginine c. Histidine d. Lysine e. Tryptophan
13. A patient is rushed to the emergency room and has suffered severe blood loss. Patient is type AB but is in short supply. The medical personnel commenced the transfusion. Which of the following reasons is correct to support the action? a. any blood type can be collected and transfused to the patient b. a blood from a pig donor will suffice c. they paid a donor with type AB millions of pesos d. all the choices are incorrect
5. A U-40 syringe is broken into, meaning each line measures 1 I ?
refer to the picture explain in detail the type of centrifugation which you will use to seperate imunoglobulin M and immunoglobulin G
2. The cytoplasm of these cells have large dark granules that contain heparin and histamine: 2. Neutrophils b, Eosinaphils ¢ Basophils d. Monocyzes
3. Draw an IgG antibody. Label the following: a. The heavy and light chains b. The constant and variable domains c. The Fab and Fc domains d. The antigen binding site, e. The hinge region f. The amino and carboxyl termini g. Indicate approximately the location of critical glycosylation sites h. Indicate approximately where the CDR (hypervariable domains) are located
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