5) Snake venom surprisingly has been a found to be a rich source of biologically active peptides. One important class potentiating peptides which were the precursors to today's most commonly used antihypertensive drugs such as captopril or lisinopril. Let's say that you are investigating a new peptide in the bradykinin potentiating peptide class from Agkistrodon bilineatus (Mexican pit viper) venom. You suspect that the peptide has the following sequence: peptides includes the bradykinin QWAQGRAPHPP After some harrowing experiments, you've collected and isolated a sample of this peptide. How will you confirm that the sequence is what you expected? Describe a sequence of chemical tests (at least 4) that you can do on this peptide that should give you enough information to deduce the sequence. Be sure to describe in detail each of the chemical analyses and the expected results of each.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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5) Snake venom surprisingly has been a found to be a rich source of biologically
active peptides. One important class of peptides includes the bradykinin
potentiating peptides which were the precursors to today's most commonly
used antihypertensive drugs such as captopril or lisinopril. Let's say that you
are investigating a new peptide in the bradykinin potentiating peptide class
from Agkistrodon bilineatus (Mexican pit viper) venom. You suspect that the
peptide has the following sequence:
QWAQGRAPHPP
After some harrowing experiments, you've collected and isolated a sample of this peptide. How will you
confirm that the sequence is what you expected? Describe a sequence of chemical tests (at least 4) that
you can do on this peptide that should give you enough information to deduce the sequence. Be sure to
describe in detail each of the chemical analyses and the expected results of each.
Transcribed Image Text:5) Snake venom surprisingly has been a found to be a rich source of biologically active peptides. One important class of peptides includes the bradykinin potentiating peptides which were the precursors to today's most commonly used antihypertensive drugs such as captopril or lisinopril. Let's say that you are investigating a new peptide in the bradykinin potentiating peptide class from Agkistrodon bilineatus (Mexican pit viper) venom. You suspect that the peptide has the following sequence: QWAQGRAPHPP After some harrowing experiments, you've collected and isolated a sample of this peptide. How will you confirm that the sequence is what you expected? Describe a sequence of chemical tests (at least 4) that you can do on this peptide that should give you enough information to deduce the sequence. Be sure to describe in detail each of the chemical analyses and the expected results of each.
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