6. The function of allelic exclusion is an increase in the ................of antibodies?.A.sensitivityB.diversityC. specificityD. affinityE. magnitude7. The specificity of antibody secreted by a B-cell may not be the same as that of thesurface Ig of the clonal parent because of:A Class switchingB Somatic hypermutationD Alternative splicingE DNA recombinationC Allelic exclusion

Answered: 6. The function of allelic exclusion is…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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6. The function of allelic exclusion is an increase in the ................of antibodies?.
A.sensitivity
B.
diversity
C. specificity
D. affinity
E. magnitude
7. The specificity of antibody secreted by a B-cell may not be the same as that of the
surface Ig of the clonal parent because of:
A Class switching
B Somatic hypermutation
D Alternative splicing
E DNA recombination
C Allelic exclusion

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One allele of a gene is expressed while the other allele is silenced through the process of allelic exclusion. Allelic exclusion, which enables each mature B lymphocyte to express only one type of immunoglobulin, allows for this phenomenon to play a part in the development of B lymphocytes, which is why it is so notable.

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