6. Retinal is a conjugated chromophore that is responsible for our ability to see. Retinal is covalently bound to the protein Rhodopsin through a lysine residue. CHO Rhodopsin |NH2 + 6.1 Draw a non-enzymatic mechanism to describe the formation of the imine between retinal and lysine. For simplicity, use R-NH2 to represent lysine. 6.2 During the visual cycle, retinal absorbs a photon and this leads to a conformation change. The bond between retinal and the protein is hydrolyzed and retinal is disconnected from the protein. Draw an arrow-pushing mechanism describing this hydrolysis step (remember that this is the reverse reaction for imine formation).
6. Retinal is a conjugated chromophore that is responsible for our ability to see. Retinal is covalently bound to the protein Rhodopsin through a lysine residue. CHO Rhodopsin |NH2 + 6.1 Draw a non-enzymatic mechanism to describe the formation of the imine between retinal and lysine. For simplicity, use R-NH2 to represent lysine. 6.2 During the visual cycle, retinal absorbs a photon and this leads to a conformation change. The bond between retinal and the protein is hydrolyzed and retinal is disconnected from the protein. Draw an arrow-pushing mechanism describing this hydrolysis step (remember that this is the reverse reaction for imine formation).
Chapter11: Reactions Of Alkyl Halides: Nucleophilic Substitutions And Eliminations
Section11.SE: Something Extra
Problem 79AP
Related questions
Question
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 2 steps with 1 images
Recommended textbooks for you
Organic Chemistry
Chemistry
ISBN:
9781305580350
Author:
William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:
Cengage Learning
Macroscale and Microscale Organic Experiments
Chemistry
ISBN:
9781305577190
Author:
Kenneth L. Williamson, Katherine M. Masters
Publisher:
Brooks Cole
Organic Chemistry
Chemistry
ISBN:
9781305580350
Author:
William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:
Cengage Learning
Macroscale and Microscale Organic Experiments
Chemistry
ISBN:
9781305577190
Author:
Kenneth L. Williamson, Katherine M. Masters
Publisher:
Brooks Cole