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- The sensitivity of a tumor to radiotherapy is related to its proximity to capillary blood supplywhile cells in the G0/G1 are less sensitive to drugs targeting DNA replication than than cells in S phase. Group of answer choices True FalseTNF and Fas ligand bind cell-surface receptors to trigger cell death. Although the death signal is generated external to the cell, why do we consider the death induced by these molecules to be apoptotic rather than necrotic?In a simple sentence, can you
- L A Moving to another question will save this response. Question 5 Select the correct statements 0 An oncogene is a cancer producing gene A proto-oncogene is only found in cancer cells Tumor suppressor genes are genes whose normal products inhibit cell division A proto-oncogene is a normal cellular gene that has the potential to become an oncogene A Moving to another question will save this response.Draw a Diagram that represents the process involved in DNA replication & Draw a Diagram that represents the operons described above.HIV is not an oncogenic virus, but it does allow for other viruses to affect oncogenes. How do viruses cause cancer progression at the cell level and how does cancer progress.
- A mutation in the Ras protein could directly affect improper _____ Select one: a. cell signaling leading to alterations in cell division b. cell signaling leading to alterations proteasome activity c. microtubule assembly leading to faulty cell division d. protein degradation during the cell cycle e. protein phosphorylation in the cell cycleIt has been suggested from study of cell cultures in a lab setting (not demonstrated in living tissue within a human) that an mRNA vaccine can produce short segments of DNA by reverse transcription. At any given time, trillions of viruses are active in a human body and viral DNA is added to the human genome by these viruses. How much viral DNA is present in the average young adult? How does this viral DNA affect the functioning of the cell/tissue/system/human? Is it permanent? ExplainWhat is the difference between a proto-oncogene and an oncogene? a. oncogenes cause benign tumors (polyps), proto-oncogenes cause malignant tumors b. oncogenes transform cells to hyperproliferation, proto-oncogenes have a normal cellular role c. oncogenes have undergone post-translational modification, proto-oncogenes have not d. oncogenes have undergone intron splicing, proto-oncogenes have not
- The cell enters g1 and cyclin D binds with CDK4/6 Increases in cyclin D expression prevent p21/p27 from inhibiting cyclin E/CDK2 Rb is hypo-phosphorylated E2F is no longer repressed and induces expression of E2F and cyclin E The cell enters S phase and cyclin A binds to CDK2 cyclin A binds to CDC 2 > Cell enters G2 and cyclin B binds CDC 2 Cell enters M phase and proliferates Put these in the correct order from 1-8A defective gene on chromosome 15 causes Tay-Sachs disease. It is a central nervous system neurodegenerative disease that most often affects infants, though older children and adults can have late-onset forms of the disease. The defective gene prevents the body from making a protein called hexosaminidase A. Without, hexosaminidase A, chemicals called gangliosides build up in the nerve cells of the brain, destroying brain cells. If individuals II-1 and II-2 have another child, what is the probability they will have a child affected by Tay-Sachs? Select one: a. 0.00 b. 0.25 c. 0.50 d. 1.00SCENARIO: MM, a 54-year old female presents to the Family Medicine Clinic due to a 2-week history of increasing shortness of breath and cough and mild/moderate pain in left side. She was diagnosed with infiltrating intraductal adenocarcinoma of the left breast 5 years ago; at that time, ER(-)/ PR(-); her-2/neu(+); p53(+); staged as having T3N1M0, stage IIIA, high-risk breast cancer. She underwent a modified radical mastectomy with axillary node dissection followed by 6 cycles of CMF chemotherapy. Her mother and sister also had a history of breast cancer. Past Medical History Gravida 4, para 4; menses onset age 13; HTN x 10 years; Type 2 DM x 8 years; breast CA described above; remained disease free until present follow up. Past Surgical History: Left modified radical mastectomy 5 years ago; cholecystectomy 14 years ago. Medications: Glyburide, 5mg PO BID Verapamil SR, 240mg PO daily Furosemide, 40mg PO daily Allergies: NKDA Physical Examination: GEN: Well-developed, obese…
