5'GGT ACG TTG GGG CTC CAT3' This sequence is transcribed and translated. If the G that is underlined changes to to a C the result will be A) A nonsenese mutation. B) A frameshift mutation C) A silent substitution. D) A missense mutation
5'GGT ACG TTG GGG CTC CAT3' This sequence is transcribed and translated. If the G that is underlined changes to to a C the result will be A) A nonsenese mutation. B) A frameshift mutation C) A silent substitution. D) A missense mutation
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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
Transcribed Image Text:**Genetic Mutations and Genetic Code Analysis**
**1. Sequence Mutation Analysis:**
**Sequence:**
5’GGT ACG TTG GGG CTC CAT3’
This sequence is transcribed and translated.
**Question 1:**
If the G that is underlined changes to a C, the result will be:
- A) A nonsense mutation
- B) A frameshift mutation
- C) A silent substitution
- D) A missense mutation
**Question 2:**
If the G that is underlined is deleted, the result will be:
- A) A nonsense mutation
- B) A frameshift mutation
- C) A silent substitution
- D) A missense mutation
**2. Gene Length and Protein Analysis:**
**Question:**
If there are 3000 bases in the coding region of a gene, the gene will have:
- A) 3000 amino acids
- B) 6000 amino acids
- C) 1000 amino acids
- D) 3000 codons
---
**Explanation of Concepts:**
- **Nonsense Mutation:** A mutation that introduces a premature stop codon, leading to truncated proteins.
- **Frameshift Mutation:** Caused by insertions or deletions that change the reading frame of the genetic sequence.
- **Silent Substitution:** A mutation that does not change the encoded amino acid.
- **Missense Mutation:** A mutation that results in a different amino acid being incorporated into the resulting protein.
- **Codons:** Groups of three bases in mRNA that code for a specific amino acid.
- **Amino Acids:** Building blocks of proteins; typically, one codon corresponds to one amino acid. In a typical gene, each set of three nucleotides (a codon) codes for one amino acid. Thus, 3000 bases would normally translate into 1000 amino acids.
![**DNA Sequence Transcription and Translation Exercise**
**Sequence 1:**
5’GGT ACG TTG GGG CTC CAT3’
This sequence is transcribed and translated. Write the resulting amino acid sequence using the 3-letter code. Write the answer in all capital letters. Leave a space between the amino acids. Do not write 5' and 3'.
[__________]
---
**Mutation Analysis:**
**Original Sequence:**
5’GGT ACG TTG GGG CTC CAT3’
This sequence is transcribed and translated.
**1. Mutation Scenario 1:**
If the G in bold changes to a T, then the result will be:
- ( ) A) A nonsense mutation
- ( ) B) A frameshift mutation
- ( ) C) A silent substitution
- ( ) D) A missense mutation
**2. Mutation Scenario 2:**
If the G in bold changes to an A, then the result will be:
- ( ) A) A nonsense mutation
- ( ) B) A frameshift mutation
- ( ) C) A silent substitution
- ( ) D) A missense mutation
---
**Instructions:**
Explore the potential impacts of point mutations in this DNA sequence. Consider how changes at specific sites might affect the resulting protein.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fa9cd2153-450c-49ea-90bd-2f7e9d0151fd%2F234f483e-9a24-4c35-b75a-86ba0ef3684e%2Fp72hrc5_processed.jpeg&w=3840&q=75)
Transcribed Image Text:**DNA Sequence Transcription and Translation Exercise**
**Sequence 1:**
5’GGT ACG TTG GGG CTC CAT3’
This sequence is transcribed and translated. Write the resulting amino acid sequence using the 3-letter code. Write the answer in all capital letters. Leave a space between the amino acids. Do not write 5' and 3'.
[__________]
---
**Mutation Analysis:**
**Original Sequence:**
5’GGT ACG TTG GGG CTC CAT3’
This sequence is transcribed and translated.
**1. Mutation Scenario 1:**
If the G in bold changes to a T, then the result will be:
- ( ) A) A nonsense mutation
- ( ) B) A frameshift mutation
- ( ) C) A silent substitution
- ( ) D) A missense mutation
**2. Mutation Scenario 2:**
If the G in bold changes to an A, then the result will be:
- ( ) A) A nonsense mutation
- ( ) B) A frameshift mutation
- ( ) C) A silent substitution
- ( ) D) A missense mutation
---
**Instructions:**
Explore the potential impacts of point mutations in this DNA sequence. Consider how changes at specific sites might affect the resulting protein.
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