5. Since in this patient pyruvate kinase is abnormal not only is less pyruvate made but intermediates above pyruvate in the glycolytic pathway build up slowing the pathway. Which of the following products may not be made in the appropriate amounts in the RBC because of the deficiency of pyruvate A. Glucose B. Oxaloacetate ? C. acetyl-CoA D. Lactate
5. Since in this patient pyruvate kinase is abnormal not only is less pyruvate made but intermediates above pyruvate in the glycolytic pathway build up slowing the pathway. Which of the following products may not be made in the appropriate amounts in the RBC because of the deficiency of pyruvate A. Glucose B. Oxaloacetate ? C. acetyl-CoA D. Lactate
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question

Transcribed Image Text:5-6. Choose the best answer from the following questions and provide a one paragraph explanation for your
response.
5. Since in this patient pyruvate kinase is abnormal not only is less pyruvate made but intermediates above
pyruvate in the glycolytic pathway build up slowing the pathway. Which of the following products may not be
made in the appropriate amounts in the RBC because of the deficiency of pyruvate
A. Glucose
?
B. Oxaloacetate
C. acetyl-CoA
D. Lactate
Explanation for answer in no. 5:
6. In the RBCS of the patient described above, which of the following would be expected
A. ADP to ATP ratios would be elevated above normal.
B. NADP+ would increase relative to NADPH.
?
C. Ribulose 5-phosphate levels would decrease.
D. NADH to NAD+ ratios would decrease.
E. Methemoglobin levels would increase.
Explanation for answer in no. 6:
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