5. DNA is made of two strands that are antiparallel. If one strand runs from 3' to 5' direction the other one will go from 5' to 3' direction. During replication or transcription, whatever the process is, it will always follow the 5' to 3' direction using the 3' to 5' directed strand as the template strand. Therefore, if following is the DNA sequence 5'-CCG ATC GCA CAA-3’ a) Using this sequence as template after transcription no protein can be translated. Why? I. Presence of start codon II. Absence of start codon III. Due to mutation b) If you want to start the translation, what change you need in the second codon (from 5' to 3' direction)? I. Substitution of C with G II. No change III. Deletion of C IV. Both I & III

Human Anatomy & Physiology (11th Edition)
11th Edition
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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5. DNA is made of two strands that are antiparallel. If one strand
runs from 3' to 5' direction the other one will go from 5' to 3'
direction. During replication or transcription, whatever the
process is, it will always follow the 5' to 3' direction using the 3'
to 5' directed strand as the template strand. Therefore, if following
is the DNA sequence
5'-CCG ATC GCA CAA-3'
a) Using this sequence as template after transcription no protein
can be translated. Why?
I. Presence of start codon
II. Absence of start codon
III. Due to mutation
b) If you want to start the translation, what change you need in the
second codon (from 5' to 3' direction)?
I. Substitution of C with G
II. No change
III. Deletion of C
IV. Both I & III
Transcribed Image Text:5. DNA is made of two strands that are antiparallel. If one strand runs from 3' to 5' direction the other one will go from 5' to 3' direction. During replication or transcription, whatever the process is, it will always follow the 5' to 3' direction using the 3' to 5' directed strand as the template strand. Therefore, if following is the DNA sequence 5'-CCG ATC GCA CAA-3' a) Using this sequence as template after transcription no protein can be translated. Why? I. Presence of start codon II. Absence of start codon III. Due to mutation b) If you want to start the translation, what change you need in the second codon (from 5' to 3' direction)? I. Substitution of C with G II. No change III. Deletion of C IV. Both I & III
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