37. Look at this pedigree and circle each row yes/no. Any assumption (that is not outrageous) can be made) for example, can assume someone is a carrier.
Given question pedigree chart is an Autosomal Dominant Inheritance because
As in the case of an autosomal dominant trait, it is required to express 1 copy of the dominant allele. And hence the trait cannot skip a generation, a similar observation was observed in the pedigree as it is shown in the pedigree that there is no skipping of a generation that 2nd Generation offspring’s number 1 and 4 have shown the disease trait and. So, the pedigree is autosomal dominant inheritance. In contrast in an autosomal recessive trait, it is required to express 2 copies of the recessive allele. And hence the trait can skip a generation therefore pedigree cannot be an autosomal recessive inheritance.
In case autosomal domain traits pedigree it shows following mentioned characteristics inheritance
- About 50% of offspring are affected
- Affects both the gender equally
- An unaffected individual never transmits the diseases.
- Never skips the generation
- If the parent is homozygous i.e. DD (D- disease having allele) then 100% of offspring will be affected.
Hence, all the characteristics have been observed in the mentioned pedigree therefore it is an Autosomal Dominant Inheritance.
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