3.91 Tea, Coffee, and Your Immune System Researchers suspect that drinking tea might enhance the production of interferon gamma, a molecule that helps the immune system fight bacteria, viruses, and tumors. A recent study45Adapted from Kamath et. al., “Antigens in Tea-Beverage Prime Human Vγ2Vδ2 T Cells in vitro and in vivo for Memory and Non-memory Antibacterial Cytokine Responses,” Proceedings of the National Academy of Sciences, May 13, 2003. involved 21 healthy people who did not normally drink tea or coffee. Eleven of the participants were randomly assigned to drink five or six cups of tea a day, while 10 were asked to drink the same amount of coffee. After two weeks, blood samples were exposed to an antigen and production of interferon gamma was measured.46To be specific, peripheral blood mononuclear cells were cultured with the antigen alkylamine ethylalamine in an enzyme linked immunospot assay to the frequency of interferon-gamma-producing cells. The results are shown in Table 3.11 and are available in ImmuneTea. We are interested in estimating the effect size, the increase in average interferon gamma production for drinking tea when compared to coffee. Use StatKey or other technology to estimate the difference in mean production for tea drinkers minus coffee drinkers. Give the standard error for the difference and a 95% confidence interval. Interpret the result in context. Table3.11Immune system response in tea and coffee drinkers Tea 5 11 13 18 20 47 48 52 55 56 58 Coffee 0 0 3 11 15 16 21 21 38 52 we introduce a study to estimate the difference in mean immune response (as measured in the study) between tea drinkers and coffee drinkers. The data are given in Table 3.11 and are available in ImmuneTea. d) Using StatKey or other technology, construct and interpret a 99% confidence interval. (e) Based on this sample and the results in parts (c) and (d), are we 90% confident that tea drinkers have a stronger immune response? Are we 99% confident?

3.91 Tea, Coffee, and Your Immune System Researchers suspect that drinking tea might enhance the production of interferon gamma, a molecule that helps the immune system fight bacteria, viruses, and tumors. A recent study45Adapted from Kamath et. al., “Antigens in Tea-Beverage Prime Human Vγ2Vδ2 T Cells in vitro and in vivo for Memory and Non-memory Antibacterial Cytokine Responses,” Proceedings of the National Academy of Sciences, May 13, 2003. involved 21 healthy people who did not normally drink tea or coffee. Eleven of the participants were randomly assigned to drink five or six cups of tea a day, while 10 were asked to drink the same amount of coffee. After two weeks, blood samples were exposed to an antigen and production of interferon gamma was measured.46To be specific, peripheral blood mononuclear cells were cultured with the antigen alkylamine ethylalamine in an enzyme linked immunospot assay to the frequency of interferon-gamma-producing cells. The results are shown in Table 3.11 and are available in ImmuneTea. We are interested in estimating the effect size, the increase in average interferon gamma production for drinking tea when compared to coffee. Use StatKey or other technology to estimate the difference in mean production for tea drinkers minus coffee drinkers. Give the standard error for the difference and a 95% confidence interval. Interpret the result in context. Table3.11Immune system response in tea and coffee drinkers Tea 5 11 13 18 20 47 48 52 55 56 58 Coffee 0 0 3 11 15 16 21 21 38 52 we introduce a study to estimate the difference in mean immune response (as measured in the study) between tea drinkers and coffee drinkers. The data are given in Table 3.11 and are available in ImmuneTea. d) Using StatKey or other technology, construct and interpret a 99% confidence interval. (e) Based on this sample and the results in parts (c) and (d), are we 90% confident that tea drinkers have a stronger immune response? Are we 99% confident?

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

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3.91

Tea, Coffee, and Your Immune System

Researchers suspect that drinking tea might enhance the production of interferon gamma, a molecule that helps the immune system fight bacteria, viruses, and tumors. A recent study⁴⁵Adapted from Kamath et. al., “Antigens in Tea-Beverage Prime Human V_γ2_Vδ2 T Cells in vitro and in vivo for Memory and Non-memory Antibacterial Cytokine Responses,” Proceedings of the National Academy of Sciences, May 13, 2003. involved 21 healthy people who did not normally drink tea or coffee. Eleven of the participants were randomly assigned to drink five or six cups of tea a day, while 10 were asked to drink the same amount of coffee. After two weeks, blood samples were exposed to an antigen and production of interferon gamma was measured.⁴⁶To be specific, peripheral blood mononuclear cells were cultured with the antigen alkylamine ethylalamine in an enzyme linked immunospot assay to the frequency of interferon-gamma-producing cells. The results are shown in Table 3.11 and are available in ImmuneTea. We are interested in estimating the effect size, the increase in average interferon gamma production for drinking tea when compared to coffee. Use StatKey or other technology to estimate the difference in mean production for tea drinkers minus coffee drinkers. Give the standard error for the difference and a 95% confidence interval. Interpret the result in context.

Table3.11Immune system response in tea and coffee drinkers

Tea	5	11	13	18	20	47
	48	52	55	56	58
Coffee	0	0	3	11	15	16
	21	21	38	52

we introduce a study to estimate the difference in mean immune response (as measured in the study) between tea drinkers and coffee drinkers. The data are given in Table 3.11 and are available in ImmuneTea.

Using StatKey or other technology, construct and interpret a 99% confidence interval.

(e)

Based on this sample and the results in parts (c) and (d), are we 90% confident that tea drinkers have a stronger immune response? Are we 99% confident?

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