3. An unaffected man marries a woman who is a carrier for Duchenne Muscular Dystrophy, which is attributed to an X-linked gene. They have four children, one boy with Duchenne, one carrier daughter and a daughter and son who are unaffected. The child with Duchenne Muscular Dystrophy dies in childhood. The carrier daughter marries and has two children of her own, which are carriers. What is the most likely sex of these two carrier children given the fact that they are unaffected by the X-linked gene? 4. A man and woman marry. They have five children, 2 girls and 3 boys. The mother is a carrier of hemophilia, an X-linked disorder. She passes the gene on to two of the boys who died in childhood and one of the daughters is also a carrier. Both daughters marry men without hemophilia and have 3 children (2 boys and a girl). The carrier daughter has one son with hemophilia. One of the non- carrier daughter's sons marries a woman who is a carrier and they have twin daughters. What is the percent chance that each daughter will also be a carrier? 4 of

3. An unaffected man marries a woman who is a carrier for Duchenne Muscular Dystrophy, which is attributed to an X-linked gene. They have four children, one boy with Duchenne, one carrier daughter and a daughter and son who are unaffected. The child with Duchenne Muscular Dystrophy dies in childhood. The carrier daughter marries and has two children of her own, which are carriers. What is the most likely sex of these two carrier children given the fact that they are unaffected by the X-linked gene? 4. A man and woman marry. They have five children, 2 girls and 3 boys. The mother is a carrier of hemophilia, an X-linked disorder. She passes the gene on to two of the boys who died in childhood and one of the daughters is also a carrier. Both daughters marry men without hemophilia and have 3 children (2 boys and a girl). The carrier daughter has one son with hemophilia. One of the non- carrier daughter's sons marries a woman who is a carrier and they have twin daughters. What is the percent chance that each daughter will also be a carrier? 4 of

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 23QP: Describe the chromosomal alterations and phenotype of cri du chat syndrome and Prader-Willi...

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Define X-linked
3) Queen Victoria of England, who ruled from 1837-1901, is believed to have been the carrier of hemophilia. Hemophilia is an X-linked disease in which the blood is unable to form clots. Please make a Punnet Square using the scenario below and answer the following questions. Queen Victoria married a man who did not have the hemophilia trait or disease. What is the likelihood that they would have a child with hemophilia? What is the likelihood that they would have a son with hemophilia? What is the likelihood that they would have a daughter with hemophilia?
Explain the difference between X-linked recessive traits and X-linked dominant traits. What are the possibilities that a female child will be affected and express each of the traits?
State who the genetic parents are and who the gestational mother is in each of the following cases:a. A man was exposed to unknown burning chemicals and received several vaccines while serving in the U.S. military in Iraq, and abused drugs for several years before and after that. Now. he wants to become a father, but he is concerned that past exposures to toxins have damaged his sperm. His wife undergoes intrauterine insemination with sperm from the husband’s brother, who has led a calmer and healthier life b. A 26-year-old woman has her uterus removed because of cancer. However, her ovaries are intact and her oocytes are healthy. She has oocytes removed and fertilized in vitro with her husband’s sperm. Two resulting embryos are implanted into the uterus of the woman’s bestfriend.c. Max and Tina had a child by IVF and froze three extra embryos. Two are thawed years later and implanted into the uterus of Tina’s sister, Karen. Karen’s uterus is healthy, but she has ovarian cysts that…
O. 2 Hemophilia A is an X-linked trait where blood clotting is affected due to a mutation in a clotting factor protein. Georgio has hemophilia and attends a support group where he meets Gbenga, who does not have the disease, but whose father has hemophilia. Her mother is not affected. A) If they marry, what percentage % of all their children will have hemophilia? % B) Georgio meets another woman, Maria, at the hemophilia support group. Maria also lacks the trait, but her mother has hemophilia while her father is unaffected. # 3 Would a Georgio-Maria mating provide a larger chance of having afflicted children compared to a Georgio-Gbenga mating? C) Show how you came up with your answer to B. Edit View Insert Format Tools Table 12pt ✓ 80 F3 V Paragraph ✓ $ 4 Yes or No 000 000 F4 DO LO % 5 BIUAV T² | F5 ^ MacBook Air 6 2 F6 V & 7 F7 * 8 DII F8 ( 9 DD F9 1 0 S F
Consider a couple: a woman who is homozygous for a recessive mutation that causes X-linked colorblindness, and a man with full color vision (he does not carry a copy of the mutation). a) What is the probability that a son of this couple will be colorblind? b) What is the probability that a daughter of the couple will be colorblind?
An individual with 46, XX genotype is diagnosed with Duchenne-type Muscular Dystrophy, a recessive X-linked disorder. Genetic tests confirm that this individual is a heterozygote for this disorder. Briefly, but specifically, explain how it’s possible that they are showing symptoms of this disorder.
Can a son be a carrier for an X-linked trait? Explain.
A man with X-linked color blindness marries a woman with no history of color blindness in her family. The daughter of this couple marries a normal man, and their daughter also marries a normal man. What is the chance that this last couple will have a child with color blindness? If this couple has already had a child with color blindness, what is the chance that their next child will be color blind?
Explain X-linked genetic inheritance.
In humans, the genes for red-green color blindness (R = normal, r = color blind) and hemophilia A (H = normal, h = hemophilia) are both X-linked and only 3 map units apart. Suppose a woman has four sons, and two are color blind but have normal blood clotting and two have hemophilia but normal color vision. What is the probable genotype of the woman? HR/hr Hr/hr hr/hR Hr/hR HR/Hr
One type of chronic porphyria is X-linked dominant. A woman with chronic porphyria whose father was normal has children with a normal man. What is the phenotypic ratio of their children? Oa. 1 female with porphyria: 1 normal male Ob. all of their children have porphyria O c 2 normal females: 1 normal male: 1 male with porphyria O d. 1 nomal female: 1 female with porphyria: 1 normal male: 1 male with porphyria O e. 2 females with porphyria: 1 male with porphyria: 1 normal male Of. all children are normal Next page Follow LIO MacBook Air DII F9 FB F7 80 F5 F3 esc F2 % 2# $ 8 6 4 この