2. The reaction shown below was performed as part of a research program funded by the National Institute of Health (NIH) to develop therapeutic agents for the treatment of cocaine addiction. ● ● H ● H- H 1₂ H HO O H O NaHCO3 1 sodium bicarbonate = mild base Using what you have learned in Chapter 8 about the addition reactions of halogens with alkenes draw a complete arrow-pushing mechanism for this process to include the following: FO obranysl Show all arrows for each mechanistic step, to illustrate correct electron flow Structures of all reaction intermediates formed in the mechanism must be shown correctly, including the key cyclic iodonium ion intermediate Underline the iodonium ion intermediate that is formed in the reaction Stereochemistry of reaction intermediates consistent with the product stereochemistry shown Formal charges where applicable
2. The reaction shown below was performed as part of a research program funded by the National Institute of Health (NIH) to develop therapeutic agents for the treatment of cocaine addiction. ● ● H ● H- H 1₂ H HO O H O NaHCO3 1 sodium bicarbonate = mild base Using what you have learned in Chapter 8 about the addition reactions of halogens with alkenes draw a complete arrow-pushing mechanism for this process to include the following: FO obranysl Show all arrows for each mechanistic step, to illustrate correct electron flow Structures of all reaction intermediates formed in the mechanism must be shown correctly, including the key cyclic iodonium ion intermediate Underline the iodonium ion intermediate that is formed in the reaction Stereochemistry of reaction intermediates consistent with the product stereochemistry shown Formal charges where applicable
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:2. The reaction shown below was performed as part of a research program funded by the National
Institute of Health (NIH) to develop therapeutic agents for the treatment of cocaine addiction.
●
HT
●
H
1₂
NaHCO3
↑
sodium bicarbonate = mild base
H
AFH
O
HO O
Using what you have learned in Chapter 8 about the addition reactions of halogens with
alkenes draw a complete arrow-pushing mechanism for this process to include the following:
Show all arrows for each mechanistic step, to illustrate correct electron flow
Structures of all reaction intermediates formed in the mechanism must be shown correctly,
including the key cyclic iodonium ion intermediate
Underline the iodonium ion intermediate that is formed in the reaction
Stereochemistry of reaction intermediates consistent with the product stereochemistry shown
Formal charges where applicable
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