2. The following 6 pedigrees were determined to show linkage to a trait: Pedigree A: LOD = 1.8 Pedigree B: LOD = 2.2 Pedigree D: LOD = -1.2 Pedigree E: LOD = -2.2
2. The following 6 pedigrees were determined to show linkage to a trait: Pedigree A: LOD = 1.8 Pedigree B: LOD = 2.2 Pedigree D: LOD = -1.2 Pedigree E: LOD = -2.2
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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2. The following 6 pedigrees were determined to show linkage to a trait:
Pedigree A: LOD = 1.8
Pedigree D: LOD = -1.2
Pedigree B: LOD = 2.2
Pedigree E: LOD = -2.2
Pedigree C: LOD = 1.0
Pedigree F: LOD = -0.6
A. What is the estimated overall evidence for linkage in these combined families?
B. Which pedigree(s) can be conclusively excluded from being linked to these
markers?
C. How much more likely is linkage in the pedigrees with positive LOD scores
than the families with negative LOD scores?
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