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Description: 2 Problem 4: Consider the pedigree of a rare autosomal trait shown below. What is the probability that IV-1 isheterozygous?13II345II13.48.IV01/301/4O2/30 1/801

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Problem 4: Consider the pedigree of a rare autosomal trait shown below. What is the probability that IV-1 is heterozygous? 1 3. 5 II 1 4 5 7. 8. IV 01/3 01/4 O 2/3 O 1/8 01

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter5: Unit, Percentage, Milliequivalent, Ratio, And Household Measures

Section: Chapter Questions

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A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.

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Problem 4: Consider the pedigree of a rare autosomal trait shown below. What is the probability that IV-1 is
heterozygous?
1
3
II
3
4
5
II
1
3.
4
8.
IV
01/3
01/4
O2/3
0 1/8
01

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Problem 2: The accompanying pedigree is for a rare, but relatively mild, hereditary disorder of the skin. 11 III IV OT 1 2 4 4 5 6 7 5 6 7 8 a. Is the disorder inherited as a recessive or a dominant phenotype? State reasons for your answer. b. Give genotypes for as many individuals in the pedigree as possible. (Invent your own defined allele symbols.) Consider the four unaffected children of parents III-4 and III-5. In all four-child progenies from parents of these genotypes, what proportion is expected to contain all unaffected children?
Problem 6: The accompanying pedigree was obtained for a rare kidney disease. $ 8 8 00 a. Deduce the inheritance of this condition, stating your reasons. b. If individuals 1 and 2 marry, what is the probability that their first child will have the kidney disease? Problem 7: Consider the accompanying pedigree of a rare autosomal recessive disease, PKU. 11 III IV B 4 a. List genotypes of as many of the family members as possible. b. If individuals A and B marry, what is the probability that their first child will have PKU? If their first child is normal, what is the probability that their second child will have PKU? If their first child has the disease, what is the probability that their second child will be unaffected?
Problem 7: Consider the accompanying pedigree of a rare autosomal recessive disease, PKU. I 11 IV 4 a. List genotypes of as many of the family members as possible. b. If individuals A and B marry, what is the probability that their first child will have PKU? If their first child is normal, what is the probability that their second child will have PKU? If their first child has the disease, what is the probability that their second child will be unaffected?
PEDIGREES: Problem 5 This pedigree shows the inheritance of sickle cell anemia in this family. I ••• QUESTIONS • • 1. How children do II-I and many 1 2 II-2 have? II O 2. What is the relationship between individuals III-2 & II-4? 2 3 4 III 3. Individual IV-I is a normal male. Drag i drop the correct shape for them: 1 2 3 IV 1
PROBLEM SOLVING: 1. What is the probability of a woman who will have 5 children giving to four girls and 1 boy in that order? (Apply product or Sum Law of Probability). 5 points 2. If two parents, both heterozygous carriers of the autosomal recessive gene causing cystic fibrosis, have five children, what is the probability that exactly three will be normal? (Use binomial formula) 5 points
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Problem 9: Albinism is inherited as an autosomal recessive. In the figure below, assuming that persons from the general population are not heterozygous for albinism (Aa), what are the genotypes of all persons whose genotypes are known? (i.e., indicate the genotypes on the figure for all known AA, Aa, and aa individuals) 어ㅁ ㅁㅇㅇㅁ 라이 ㅇㅇㅇㅇㅇㅇㅇㅇㅇㅇㅇㅁ ㅇㅇㅁㅁ 58 o
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tion 8: below is the pedigree of inheritance of phenylketonuria (PKU). We will designate the letter Caven for the dominant allele and "p" for the recessive allele. 4 The pedigree shows that the pattern of inheritance for the allele for phenylk ylketonuria is: I. II. 1 III. IV. Autosomal dominant Autosomal recessive X-linked dominant X-linked recessive b. The parents in generation I have how many children: I. 3 Boys II. 3 Girls III. IV. 3 Boys and 1 Girl 3 Girls and 1 Boy c. What is the genotype of individual 1 in generation III: I. PP II. pp III. Pp " O 1 III. 50% E III 1 ▬ 2 2 IV. 25% 1 3 IV. Can be PP or Pp ii. Suppose that a man having type AB blood marries a woman having type O blood. What is the probability that their child will have type A blood? I. 100% II. 75% 2 4 3
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