Answered: Problem 4: Consider the pedigree of a…

Name: 2 Problem 4: Consider the pedigree of a rare autosomal trait shown bel
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: 2 Problem 4: Consider the pedigree of a rare autosomal trait shown below. What is the probability that IV-1 isheterozygous?13II345II13.48.IV01/301/4O2/30 1/801

Science

Biology

Problem 4: Consider the pedigree of a rare autosomal trait shown below. What is the probability that IV-1 is heterozygous? 1 3. 5 II 1 4 5 7. 8. IV 01/3 01/4 O 2/3 O 1/8 01

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter5: Unit, Percentage, Milliequivalent, Ratio, And Household Measures

Section: Chapter Questions

Problem 12SST

See similar textbooks

Related questions

Q: FLG I_ K

A: Human muscular system:The muscular system is made out of particular specialized cells known as…

Q: بار در انبار الدولة ر

A: The ECG or electrocardiogram is a test that is used to detect the heart rhythm and electrical…

Q: 30 29 27 26 25 24 23 21 22 20 19 18 17 16 1 15

A: From the mouth to the anus, the digestive system is made up of a collection of hollow organs…

Q: stroke & Normal pregnacy( antenatal monitoring)

A: Stroke is a medical condition that occurs when the blood supply to part of the brain is interrupted…

Q: When part of a nucleotide in a nucleic acid chain, which of the following may base pair with uridine…

A: Uridine is a major form of pyrimidine nucleotide, from which cytosine and uracil are derived. It is…

Q: 44 43 42 Medial (Ulnar) View

A: for the above image

Q: Figure 8.12 In the accompanying figure, the green rectangular shape represents_ O a. DNA…

A: All genetic information are stored in DNA, which is present in nucleus in case of eukaryotic cell…

Q: Sequelae definition

A: When activity of one or more organ is disrupted then it is characterized by sign and symptoms,this…

Q: Hematology exam

A: Hematology is the study of blood and blood disorders. Those who perform this study are called…

Q: This represents a cell undergoing meiosis. Which phase of meiosis does this represent?

A: Meiosis is a mechanism in which a single cell divides twice to create four cells with half the…

Q: Which of the following does not serve the function of contributing to the composition of semen? O A…

A: The production of semen in the human male is a long drawn out process that happens with the…

Q: Intracranial shunts

A: A shunt is a small passage or a hole which moves or allows the movement of the fluids from one site…

Concept explainers

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.

Topic Video

Question

Problem 4: Consider the pedigree of a rare autosomal trait shown below. What is the probability that IV-1 is
heterozygous?
1
3
II
3
4
5
II
1
3.
4
8.
IV
01/3
01/4
O2/3
0 1/8
01

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

step 2

Step 3

Step 4

Step 5

Step 6

Trending now

This is a popular solution!

Step by step

Solved in 6 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.

Similar questions

Mike was referred for genetic counseling because he was concerned about his extensive family history of colon cancer. That family history was highly suggestive of hereditary nonpolyposis colon cancer (HNPCC). This predisposition is inherited as an autosomal dominant trait, and those who carry the mutant allele have a 75% chance of developing colon cancer by age 65. Mike was counseled about the inheritance of this condition, the associated cancers, and the possibility of genetic testing (on an affected family member). Mikes aunt elected to be tested for one of the genes that may be altered in this condition and discovered that she did have an altered MSH2 gene. Other family members are in the process of being tested for this mutation. Seventy-five percent of people who carry the mutant allele will get colon cancer by age 65. This is an example of incomplete penetrance. What could cause this?
Mike was referred for genetic counseling because he was concerned about his extensive family history of colon cancer. That family history was highly suggestive of hereditary nonpolyposis colon cancer (HNPCC). This predisposition is inherited as an autosomal dominant trait, and those who carry the mutant allele have a 75% chance of developing colon cancer by age 65. Mike was counseled about the inheritance of this condition, the associated cancers, and the possibility of genetic testing (on an affected family member). Mikes aunt elected to be tested for one of the genes that may be altered in this condition and discovered that she did have an altered MSH2 gene. Other family members are in the process of being tested for this mutation. Once a family member is tested for the mutant allele, is it hard for other family members to remain unaware of their own fate, even if they did not want this information? How could family dynamics help or hurt this situation?
Mike was referred for genetic counseling because he was concerned about his extensive family history of colon cancer. That family history was highly suggestive of hereditary nonpolyposis colon cancer (HNPCC). This predisposition is inherited as an autosomal dominant trait, and those who carry the mutant allele have a 75% chance of developing colon cancer by age 65. Mike was counseled about the inheritance of this condition, the associated cancers, and the possibility of genetic testing (on an affected family member). Mikes aunt elected to be tested for one of the genes that may be altered in this condition and discovered that she did have an altered MSH2 gene. Other family members are in the process of being tested for this mutation. Is colon cancer treatable? What are the common treatments, and how effective are they?
State whether each of the following genetic defects is inherited as an autosomal recessive, autosomal dominant, or X-linked recessive trait: phenylketonuria (PKU), sickle cell anemia, cystic fibrosis, Tay-Sachs disease, Huntingtons disease, and hemophilia A.
A couple has had a child born with neurofibromatosis. They come to your genetic counseling office for help. After taking an extensive family history, you determine that there is no history of this disease on either side of the family. The couple wants to have another child and wants to be advised about the risks of that child having neurofibromatosis. What advice do you give them?
Genetics in Practice case studies are critical-thinking exercises that allow you to apply your new knowledge of human genetics to real-life problems. Case study Michelle was a 42-year-old woman who had declined counselling and amniocentesis at 16 weeks of pregnancy but was referred for genetic counseling after an abnormal ultrasound at 20 weeks of gestation. After the ultrasound, a number of findings suggested a possible chromosome abnormality in the fetus. The ultrasound showed swelling under the skin at the back of the fetuss neck; shortness of the femur, humerus, and ear length; and underdevelopment of the middle section of the fifth finger. Michelles physician performed an amniocentesis and referred her to the genetics program. Michelle and her husband did not want genetic counseling before receiving the results of the cytogenetic analysis. This was Michelles third pregnancy; she and her husband, Mike, had a 6-year-old daughter and a 3-year-old son. At their next session, the counselor informed the couple that the results revealed trisomy 21, explored their understanding of Down syndrome, and elicited their experiences with people with disabilities. She also reviewed the clinical concerns revealed by the ultrasound and associated anomalies (mild to severe intellectual disability, cardiac defects, and kidney problems). The options available to the couple were outlined. They were provided with a booklet written for parents making choices after the prenatal diagnosis of Down syndrome. After a week of careful deliberation with their family, friends, and clergy, they elected to terminate the pregnancy. Should physicians discourage a 42-year-old woman from having children because of an increased chance of a chromosomal abnormality?
Marfan syndrome is inherited in an autosomal dominant pattern. Which of the following is true? Female offspring are more Likely to be carriers of the disease. Male offspring are more likely to inherit the disease. Male and female offspring have the same likelihood of inheriting the disease. Female offspring are more likely to inherit the disease.
How can a female carrier of an X-linked recessive disorder have a daughter who is affected?
Which of the following terms means many genes? polymorphism polygeny polypeptide multiple alleles
Why is it more efficient to perform a test cross with a homozygous recessive donor than a homozygous dominant donor? How could the same information still he found with a homozygous dominant donor?
Jan is concerned about using ART. She wants to be the genetic mother and have Darryl be the genetic father of any children they have. What methods of ART would you recommend to this couple? Jan, a 32-year-old woman, and her husband, Darryl, have been married for 7 years. They have attempted to have a baby on several occasions. Five years ago, they had a first-trimester miscarriage, followed by an ectopic pregnancy later the same year. Jan continued to see her OB/GYN physician for infertility problems but was very dissatisfied with the response. After four miscarriages, she went to see a fertility specialist, who diagnosed her with severe endometriosis and polycystic ovarian disease (detected by hormone studies). The infertility physician explained that these two conditions were hampering her ability to become pregnant and thus making her infertile. She referred Jan to a genetic counselor. At the appointment, the counselor explained to Jan that one form of endometriosis (MIM 131200) can be a genetic disorder, and that polycystic ovarian disease can also be a genetic disorder (MIM 184700) and is one of the most common reproductive disorders among women. The counselor recommended that a detailed family history of both Jan and Darryl would help establish whether Jans problems have a genetic component and whether any of her potential daughters would be at risk for one or both of these disorders. In the meantime, Jan is taking hormones, and she and Darryl are considering alternative modes of reproduction. Using the information in Figure 16.4, explain the reproductive options that are open to Jan and Darryl.
For most cases, a p value of 0.05 is used to determine whether results fit expected values. Is this a magic number, or could p values be set more stringently, say 0.01, or more lax, say 0.10? What effect would these values have on the reliability of the chi-square test?