Anatomy & Physiology
1st Edition
ISBN: 9781938168130
Author: Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher: OpenStax College
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Textbook Question
Chapter 28, Problem 28RQ
Marfan syndrome is inherited in an autosomal dominant pattern. Which of the following is true?
- Female offspring are more Likely to be carriers of the disease.
- Male offspring are more likely to inherit the disease.
- Male and female offspring have the same likelihood of inheriting the disease.
- Female offspring are more likely to inherit the disease.
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Students have asked these similar questions
Q1: What is the probability that a child with one parent who has an autosomal dominant disorder will inherit the disease? Q2: Why are there no carriers with a dominant genetic disorder? Q3: Because dominant genetic disorders are rare, it is extremely rare for both parents to have the condition (genotype Aa). Draw a Punnett square with two Aa parents. What proportion of the offspring would have the disorder? What proportion would be normal?
Answer the question(s) in reference to the five disorders listed below:
Hutchtinson-Gilford progeria
hemophilia
turner syndrome
down syndrome
klinefelter syndrome
Among the following, which inheritance pattern increases the occurrence of the
disease?
Autosomal dominant
Sex linked dominant
Mitochondrial
O Autosomal recessive
Chapter 28 Solutions
Anatomy & Physiology
Ch. 28 - View this time-lapse movie...Ch. 28 - Visit this site...Ch. 28 - Sperm and ova are similar in terms of ________....Ch. 28 - Although the male ejaculate contains hundreds of...Ch. 28 - As sperm first reach the oocyte, they will contact...Ch. 28 - Fusion of pronuclei occurs during ________....Ch. 28 - Sperm must first complete ________ to enable the...Ch. 28 - Cleavage produces daughter cells called ________....Ch. 28 - The conceptus, upon reaching the uterus, first...Ch. 28 - The inner cell mass of the blastocyst is destined...
Ch. 28 - Which primary germ layer gave rise to the cells...Ch. 28 - What would happen if the trophoblast did not...Ch. 28 - During what process does the amnion envelop the...Ch. 28 - The placenta is formed from ________. the embryos...Ch. 28 - The foramen ovale causes the fetal circulatory...Ch. 28 - What happens to the urine excreted by the fetus...Ch. 28 - During weeks 9–12 of fetal development,...Ch. 28 - Progesterone secreted by the placenta suppresses...Ch. 28 - Which of the following is a possible culprit of...Ch. 28 - How does the decrease in progesterone at the last...Ch. 28 - Which of these fetal presentations is the easiest...Ch. 28 - Which of these shunts exists between the right and...Ch. 28 - Why is brown fat important? It is the newborns...Ch. 28 - Constriction of umbilical blood vessels during...Ch. 28 - Alveoli are connected to the lactiferous sinuses...Ch. 28 - How is colostrum most important to a newborn? It...Ch. 28 - Mature breast milk ________. has more sodium than...Ch. 28 - Marfan syndrome is inherited in an autosomal...Ch. 28 - In addition to codominance, the ABO blood group...Ch. 28 - Zoe has cystic fibrosis. Which of the following is...Ch. 28 - Darcy and Raul are having difficulty conceiving a...Ch. 28 - Sherrise is a sexually active college student. On...Ch. 28 - Approximately 3 weeks after her last menstrual...Ch. 28 - The Food and Nutrition Board of the Institute of...Ch. 28 - What is the physiological benefit of incorporating...Ch. 28 - Why would a premature infant requite supplemental...Ch. 28 - Devin is 35 weeks pregnant with her first child...Ch. 28 - Janine is 41 weeks pregnant with her first child...Ch. 28 - Describe how the newborns fust breath alters the...Ch. 28 - Newborns are at much higher risk for dehydration...Ch. 28 - Describe the transit of breast milk from...Ch. 28 - A woman who stopped breastfeeding suddenly is...Ch. 28 - Explain why it was essential that Mendel perform...Ch. 28 - How can a female carrier of an X-linked recessive...
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- Marfan syndrome is transmitted by a dominant gene.State the probability that a child with an affected parentwill have the disorderarrow_forwardA female that is a carrier for DMD has kids with a normal male. Show work. a) What is the chance (%) that these two parents will have a kid with DMD? b) Their first child is a son. What is the chance (%) that he will have DMD? Hint: Look at only the male offspring when you answer this question.arrow_forwardIn humans, hemophilia is a sex-linked trait. Females can be normal, carriers, or have the disease. Males will either have the disease or not (but they won’t ever be carriers). X H X H = female, non-hemophilic X H X h = female, carrier X h X h = female, hemophilia X H Y = male, non-hemophilic X h Y= male, hemophiliac a.) Show the cross of a man who has hemophilia with a woman who is a carrier. What is the probability that their children will have the disease? b.) A woman who is a carrier marries a non-hemophilic man. Show the cross. What is the probability that their children will have hemophilia? What sex will a child in the family with hemophilia be? c.) A woman who has hemophilia marries a non-hemophilic man. How many of their children will have hemophilia, and what is their sex?arrow_forward
- Huntington disease (HD) is a genetic disorder that usually first appears in middle age and, over time, leads to involuntary movements, impaired speech, difficulty swallowing and speaking, and cognitive decline. There is no cure for HD, and affected individuals eventually die, usually after 10 to 15 years of progressively worsening symptoms. Huntington disease is inherited as an autosomal dominant disorder. Presymptomatic genetic testing for HD is available for people with a family history of the disease. Individuals who have a parent with HD have a 50% chance of inheriting the HD gene and eventually having HD. Some of these individuals want to know if they will eventually get the disease, and they undergo presymptomatic genetic testing. Others do not want to know, given that there is no cure or effective treatment for the disease. If you were at risk for HD, would you want to undergo genetic testing? What are some reasons for and against having a genetic test for HD?arrow_forward2. STATEMENT: A woman and man both do not have sickle-cell anemia, but both had one parent who had sickle cell. Sickle-cell is an autosomal (somatic) recessive trait. a) What is the genotype for the woman, man and each of their parents? b) This couple unexpectedly is going to have their first child. i. What's the probability that their child will have not have sickle cell like the couple? ii. What's the probability that the child will have sickle cell like one the grandparents?arrow_forwardA patient has two parents with Huntington's disease. They may not have inherited this autosomal dominant disorder due to: 1) increased DNA repeats (CAG) during spermatogenesis 2) incomplete penetrance 3) inheriting one recessive allelearrow_forward
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