2. Consider the pre-mRNA molecule shown below. Re-order the events listed, in the sequence they would occur during pre-mRNA processing in eukaryotes. Pre-MRNA Exon 1 Intron Exon 2 Pre-MRNA processing MRNA Exon1 Exon 2 AAAAA 3 Export to cytoplasm Translation Recognition and binding the 3' AAUAAA sequence by specific proteins Attachment of snRNP U1 to the 5' splice site Formation of a bond between the guanine in the 5' splice site and the adenine of the branch point Binding of the snRNP U4, U5 and U6 complex to the spliceosome Addition of the 5' cap Release of the intron as a lariat structure and splicing of exon 1 and 2 Addition of the poly(A) tail Binding of snRNP U2 to the branch point Cleavage at the poly (A) site
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
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