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13. Properties of male and female rat nociceptors that respond to painful mechanical stimuli (for instance a sharp tack) were recently studied by Hendrich, et al. (2012). The sensory endings of these nociceptors are found on the foot of the rat. They measured resting membrane potential (RMP) (Fig 2B) and action potential threshold (Fig 2C) in the nociceptors. The results and figure legend are shown below. Use the data (attached) to answer the following questions.   a. What category of sensory afferent are the authors studying?    b. What reflex(es) does this sensory afferent participate in?   c. What conclusions can the authors make based on the data shown in this figure? Speculate on what physiological/behavioral consequences there might be based on the findings.

13. Properties of male and female rat nociceptors that respond to painful mechanical stimuli (for instance a sharp tack) were recently studied by Hendrich, et al. (2012). The sensory endings of these nociceptors are found on the foot of the rat. They measured resting membrane potential (RMP) (Fig 2B) and action potential threshold (Fig 2C) in the nociceptors. The results and figure legend are shown below. Use the data (attached) to answer the following questions.   a. What category of sensory afferent are the authors studying?    b. What reflex(es) does this sensory afferent participate in?   c. What conclusions can the authors make based on the data shown in this figure? Speculate on what physiological/behavioral consequences there might be based on the findings.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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13. Properties of male and female rat nociceptors that respond to painful mechanical stimuli (for instance a sharp tack) were recently studied by Hendrich, et al. (2012). The sensory endings of these nociceptors are found on the foot of the rat. They measured resting membrane potential (RMP) (Fig 2B) and action potential threshold (Fig 2C) in the nociceptors. The results and figure legend are shown below. Use the data (attached) to answer the following questions.

  a. What category of sensory afferent are the authors studying?

   b. What reflex(es) does this sensory afferent participate in?

  c. What conclusions can the authors make based on the data shown in this figure? Speculate on what physiological/behavioral consequences there might be based on the findings.

U (posod aunquage Female Mile Figure 2. Action potential properties of female and male noci ceptors. (A) Representative action potential traces, obtained at rheobase, from female (left) and male (right) nociceptors. The dotted lines represent RMP in both neurons for comparison. (8) RMP is significantly more hyperpolarized in female neurons than in male neurons. (C) However, the membrane potential threshold for action potential generation was not significantly different between the 2 populations. *** represents P<.001 (2-tailed t-test).
Transcribed Image Text:U (posod aunquage Female Mile Figure 2. Action potential properties of female and male noci ceptors. (A) Representative action potential traces, obtained at rheobase, from female (left) and male (right) nociceptors. The dotted lines represent RMP in both neurons for comparison. (8) RMP is significantly more hyperpolarized in female neurons than in male neurons. (C) However, the membrane potential threshold for action potential generation was not significantly different between the 2 populations. *** represents P<.001 (2-tailed t-test).
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Transcribed Image Text:A (ym) prywayəd aumsquare Bugey Female -30 Female Male Male
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