10. ATP synthase is a key enzyme of mitochondrial energy conversion. Mitochondrial ATP synthase deficiency is due to a mutation in a gene important for the formation of a subunit in the ATP synthase complex, seen in the illustration below. Scientists could use cells with this gene mutation to investigate which of the following questions? (LS1-7) * Inner mitochondrial membrane PYRUVATE GLYCOLYSS ODATION CITRIC ACO CYCLE ODATIVE PHOSPHORYL ATION ATP synthase Protein complex of electron carriers Intermembrane• space Inner mitochondrial membrane FADH, FAD 2 H* + ½02 H,0 NADH NAD ADP + P ATP (carrying electrons from food) Mitochondrial matrix Oxidative phosphorylation What effect does the mutation have on the movement of electrons between the electron carriers of the electron transport chain? What effect does the mutation have on the amount of ATP synthesized during cellular respiration? What effect does the mutation have on the number of protons pumped into the intermembrane space of the mitochondria? What effect does the mutation have on the number of water molecules formed at the end of the electron transport chain?
10. ATP synthase is a key enzyme of mitochondrial energy conversion. Mitochondrial ATP synthase deficiency is due to a mutation in a gene important for the formation of a subunit in the ATP synthase complex, seen in the illustration below. Scientists could use cells with this gene mutation to investigate which of the following questions? (LS1-7) * Inner mitochondrial membrane PYRUVATE GLYCOLYSS ODATION CITRIC ACO CYCLE ODATIVE PHOSPHORYL ATION ATP synthase Protein complex of electron carriers Intermembrane• space Inner mitochondrial membrane FADH, FAD 2 H* + ½02 H,0 NADH NAD ADP + P ATP (carrying electrons from food) Mitochondrial matrix Oxidative phosphorylation What effect does the mutation have on the movement of electrons between the electron carriers of the electron transport chain? What effect does the mutation have on the amount of ATP synthesized during cellular respiration? What effect does the mutation have on the number of protons pumped into the intermembrane space of the mitochondria? What effect does the mutation have on the number of water molecules formed at the end of the electron transport chain?
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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