Please fill in the blanks1.Antibiotics that are active against G= and G-organisms such as Blank 1, Blank 2, and Blank3 contain both proteinogenic and non-proteinogenic amino acids.2.In the structure of vancomycin, the Blank 1moiety contributes to its solubility in polarmedium3.Among the macrolides, Blank 1 was isolatedfrom a soil bacterium and had the Blank 2 saltin its formulation. Substitution of Blank 3 groupat 6 position of the hydroxyl moiety gives anew derivative, Blank 4. On the other hand,the modification of this drug via n-methylationproduces a more potent and broad-spectrumderivative Blank 5.

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Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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hello! look at the attached image which shows the the four major mechanisms of antibiotic resistance and explain it :) Thank you!!
1. Which of the following statement/s is/are TRUE for the protein sample?* The sample will give a positive result to Biuret test. All of A, B and C The sample will give a positive result to Ninhydrin test. The sample will give a positive result to Xanthoproteic test. 2. Extremely high pH causes folding of the protein molecules. * The statement is CORRECT. The statement is INCORRECT. 3.Negative with Biuret Test but positive with Ninhydrin Test, Xanthoproteic Test and Millon’s Test Glycine Tryptophan Tyrosine Methionine Albumin
1. What is the importance of using freshly prepared KOH? 2. What is the chemical constituent responsible for the acid-fast property of Mycobacterium species?
1) What is the importance of good nutrition in the efforts of containing Covid-19 Globally. (Add supporting references).
21. A drip rate is set at 20 drops/min using a 1 L D2.5W bag containing 600 mg of an antibiotic. If a 10-drop set is used, how long will it take to empty out the bag, in hours? 176 th nationt will receive 5 mca/ko/min
10. The current recommendation for the dose of amoxicillin used in the treatment of otitis media (middle ear infection) in children weighing less than 40 pounds is 90mg/kg/day administered in 3 equally divided doses. How many milliliters of Amoxil suspension 400mg/5ml should be dispensed to the patient to complete a 10-day course of therapy if the child weighs 22 pounds?
05.
1. Doesn't non-fat milk protein contain casein which interacts with the Bradford reagent. why would this react with the Bradford or Bruiet reagent? 2. Tryptophan is an amino acid and there should not be a reaction with the reagent. Why would there be a reaction with the Bradford or Biuret reagent?
All of the following are beneficial for a pathogenic bacterium, but O adhesins O fructose O endotoxin Olipid A is/are the most crucial in order for a bacterium to establish an infection.
2. Why would you expect to see no violet color when free amino acids (no peptide bonds) are mixed with Biuret reagent?
2. Consider the following paragraph from a peer-reviewed publication detailing the extraction and isolation of a lectin: "30 g of dry S. sclarea seeds were ground in a Waring blender and the meal was stirred overnight in 400 ml of Phosphate Buffered Saline (PBS), at 4 °C. The solution was centrifuged at 20,000 X g for 30 min, and the pellet was re-extracted by mixing with another 400 ml of PBS, overnight at 4°C. The two supernatants were combined and frozen at -20 °C. After thawing, the insoluble material was spun down (3,500 X g for 30 min), and the clear supernatant (crude extract) was precipitated with 50% (v/v) cold ethanol at 4 °C. After centrifugation (20,000 X g for 30 min), the pellet was discarded, and the supernatant was further precipitated with cold ethanol up to 80% (v/v) at 4 °C. After one night in the cold room, the solution was centrifuged (20,000 X g for 30 min), the supernatant was discarded, and the pellet was re-dissolved in water, dialyzed for 3 days at 4 °C…

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1.Antibiotics that are active against G= and G- organisms such as Blank 1, Blank 2, and Blank 3 contain both proteinogenic and non- proteinogenic amino acids. 2.In the structure of vancomycin, the Blank 1 moiety contributes to its solubility in polar medium