A macrolide containing a 15-membered lactone ring

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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1. A macrolide containing a 15-membered lactone ring 
 
Erythromycin
Telithromycin
Clarithromycin
Azithromycin
 
2. ALL are true about the activity of Macrolides EXCEPT: 
 
It is effective against syphilis infections
it resembles that of penicillin
it is very effective against G(-) bacteria
it is effective against erysipelas infections
 
3. These are ALL causes of bacterial resistance against macrolides EXCEPT: 
 
active efflux
bacterial endospores
release of esterases
modification of binding site
 
4. These are ALL adverse effects of Erythromycin EXCEPT: 
 
CYP450 inhibition
Hepatotoxicity
Neutropenia
Acute cholestatic hepatitis
 
5. These are drugs that have prolonged half-life when taken with erythromycin EXCEPT: 
 
Rifampicin
Lipitor
Lanoxin
Lasix
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